Phosphodiesterase

Modify Date: 2024-01-02 23:36:57

Phosphodiesterase structure	Common Name	Phosphodiesterase
	CAS Number	9025-82-5	Molecular Weight	N/A
	Density	N/A	Boiling Point	N/A
	Molecular Formula	N/A	Melting Point	N/A
	MSDS	Chinese USA	Flash Point	N/A

Use of Phosphodiesterase

Phosphodiesterase (PDE) is an enzyme that can catalyze the hydrolysis of the 3' ring phosphate bond of cyclic nucleotides, and is often used in biochemical research. Phosphodiesterase acts as an important regulator of signal transduction mediated by the second messenger molecules cAMP and cGMP. According to their specificity to cyclic nucleotides, they can also be divided into different types, such as PDE1-PDE11, which also have certain potential in various diseases[1].

Name	phosphodiesterase i
Synonym	More Synonyms

Description	Phosphodiesterase (PDE) is an enzyme that can catalyze the hydrolysis of the 3' ring phosphate bond of cyclic nucleotides, and is often used in biochemical research. Phosphodiesterase acts as an important regulator of signal transduction mediated by the second messenger molecules cAMP and cGMP. According to their specificity to cyclic nucleotides, they can also be divided into different types, such as PDE1-PDE11, which also have certain potential in various diseases[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphodiesterase (PDE) Research Areas >> Neurological Disease
References	[1]. Sébastien Delhaye, et al. Role of phosphodiesterases in the pathophysiology of neurodevelopmental disorders. Mol Psychiatry. 2021 Sep;26(9):4570-4582.

Storage condition	-20°C

RIDADR	NONH for all modes of transport
RTECS	SZ5999500

Effects of pH on the production of phosphate and pyrophosphate by matrix vesicles' biomimetics.

Calcif. Tissue Int. 93(3) , 222-32, (2013)

During endochondral bone formation, chondrocytes and osteoblasts synthesize and mineralize the extracellular matrix through a process that initiates within matrix vesicles (MVs) and ends with bone min...

Contribution of adenosine-producing ectoenzymes to the mechanisms underlying the mitigation of maternal-fetal conflicts.

J. Biol. Regul. Homeost. Agents 27(2) , 519-29, (2013)

The interactions taking place between mother and embryo have been the focus of detailed studies in recent years, where pregnancy is considered as an in vivo transplant. The immune systems of the mothe...

Inflammatory cytokines induce a unique mineralizing phenotype in mesenchymal stem cells derived from human bone marrow.

J. Biol. Chem. 288(41) , 29494-505, (2013)

Bone marrow contains mesenchymal stem cells (MSCs) that can differentiate along multiple mesenchymal lineages. In this capacity they are thought to be important in the intrinsic turnover and repair of...

ec 3.1.4.1 type iv

ec 3.1.4.1 type v

ec 3.1.4.1 type vi

ec 3.1.4.1

iub: 3.1.4.1

5'-exonuclease

5'-exonuclease type iv

5'-exonuclease type v