1-(2-Chlorobenzyl)-3-(4-nitrophenyl)thiourea
Modify Date: 2025-08-27 10:29:29
1-(2-Chlorobenzyl)-3-(4-nitrophenyl)thiourea structure
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Common Name | 1-(2-Chlorobenzyl)-3-(4-nitrophenyl)thiourea | ||
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| CAS Number | 900701-83-9 | Molecular Weight | 321.782 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 478.3±55.0 °C at 760 mmHg | |
| Molecular Formula | C14H12ClN3O2S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 243.1±31.5 °C | |
Use of 1-(2-Chlorobenzyl)-3-(4-nitrophenyl)thioureaInhA-IN-3 (Compound TU12) is a Mycobacterium tuberculosis InhA (an enoyl ACP-reductase) inhibitor with an IC50 of 17.7 μM[1]. |
| Name | 1-(2-Chlorobenzyl)-3-(4-nitrophenyl)thiourea |
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| Synonym | More Synonyms |
| Description | InhA-IN-3 (Compound TU12) is a Mycobacterium tuberculosis InhA (an enoyl ACP-reductase) inhibitor with an IC50 of 17.7 μM[1]. |
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| Related Catalog | |
| Target |
IC50: 17.7 μM (InhA)[1] |
| In Vitro | InhA-IN-3 (Compound TU12) shows antitubercular activity with a MIC of 0.78±0.59 µg/mL against Mycobacterium tuberculosis[1]. |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 478.3±55.0 °C at 760 mmHg |
| Molecular Formula | C14H12ClN3O2S |
| Molecular Weight | 321.782 |
| Flash Point | 243.1±31.5 °C |
| Exact Mass | 321.033875 |
| LogP | 3.72 |
| Vapour Pressure | 0.0±1.2 mmHg at 25°C |
| Index of Refraction | 1.709 |
| 1-(2-Chlorobenzyl)-3-(4-nitrophenyl)thiourea |
| Thiourea, N-[(2-chlorophenyl)methyl]-N'-(4-nitrophenyl)- |
| MFCD04154139 |