Parathyroid
Modify Date: 2025-08-25 19:56:37
Parathyroid structure
|
Common Name | Parathyroid | ||
|---|---|---|---|---|
| CAS Number | 9002-64-6 | Molecular Weight | N/A | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | N/A | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of ParathyroidParathyroid hormone (PTH) is a circulating hormone comprised of 84 amino acids. Parathyroid hormone is produced in the parathyroid glands and acts primarily on bone and kidney to maintain extracellular calcium levels within normal limits. Parathyroid hormone can be used for osteoporosis research[1]. |
| Name | Parathyoid |
|---|---|
| Synonym | More Synonyms |
| Description | Parathyroid hormone (PTH) is a circulating hormone comprised of 84 amino acids. Parathyroid hormone is produced in the parathyroid glands and acts primarily on bone and kidney to maintain extracellular calcium levels within normal limits. Parathyroid hormone can be used for osteoporosis research[1]. |
|---|---|
| Related Catalog | |
| Target |
Human Endogenous Metabolite |
| In Vitro | Parathyroid hormone (PTH) has biphasic effects on bone: continuous treatment is catabolic whereas intermittent treatment is anabolic[2]. Parathyroid hormone secretion can be improved by physical exercise[2]. |
| In Vivo | Parathyroid hormone (hPTH1–34) (40 μg/kg, s.c.; daily for 2 weeks) exerts a catabolic effect on mouse bone with a significant decrease in trabecular connectivity density[3]. Animal Model: 10-week-old female C57BL/J6 mice[3] Dosage: 40 μg/kg Administration: Subcutaneous injection, daily for 2 weeks Result: Significantly suppressed endogenous intact mPTH1–84 from 2.40 ± 0.55 pM (control) to 0.73 ± 0.25 pM, and significantly increased total serum calcium levels from 1.95 to 2.64 mM. |
| References |
| Storage condition | 20°C |
|---|
| MFCD00147846 |