DSM 74
Modify Date: 2024-01-11 10:40:33
DSM 74 structure
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Common Name | DSM 74 | ||
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| CAS Number | 898743-92-5 | Molecular Weight | 293.253 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C13H10F3N5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of DSM 74A potent, orally active PfDHODH inhibitor (IC50=0.3 uM) with antimalarial activity; shows good plasma exposure in mice and is equally potent against PfDHODH and PbDHODH; suppresses growth of P. berghei in mice after oral administration. |
| Name | DSM 74 |
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| Description | A potent, orally active PfDHODH inhibitor (IC50=0.3 uM) with antimalarial activity; shows good plasma exposure in mice and is equally potent against PfDHODH and PbDHODH; suppresses growth of P. berghei in mice after oral administration. |
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| References | References 1. Lukens AK, e tal. Proc Natl Acad Sci U S A. 2014 Jan 14;111(2):799-804. 2. Gujjar R, et al. J Med Chem. 2009 Apr 9;52(7):1864-72. 3. Lee JJ, et al. urr Microbiol. 2014 Sep;69(3):286-91. View Related Products by Target Bacterial |
| Molecular Formula | C13H10F3N5 |
|---|---|
| Molecular Weight | 293.253 |