F7H

Modify Date: 2024-09-24 18:39:27

F7H Structure
F7H structure
Common Name F7H
CAS Number 897109-93-2 Molecular Weight 463.55
Density N/A Boiling Point N/A
Molecular Formula C24H18FN3O2S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of F7H


F7H is a Frizzled receptor FZD7 antagonist (IC50: 1.25 μM). Frizzled receptors (FZDs) influence Wnt signaling, mediating embryonic development and tissue homeostasis. F7H is a potent ligand for the FZD7 transmembrane domain (TMD)[1].

 Names

Name F7H

 F7H Biological Activity

Description F7H is a Frizzled receptor FZD7 antagonist (IC50: 1.25 μM). Frizzled receptors (FZDs) influence Wnt signaling, mediating embryonic development and tissue homeostasis. F7H is a potent ligand for the FZD7 transmembrane domain (TMD)[1].
Related Catalog
Target

IC50: 1.25 μM (Frizzled receptor, FZD7)[1]

References

[1]. Li C, et al. Structure-Based Ligand Discovery Targeting the Transmembrane Domain of Frizzled Receptor FZD7. J Med Chem. 2023 Sep 14;66(17):11855-11868.. .  

 Chemical & Physical Properties

Molecular Formula C24H18FN3O2S2
Molecular Weight 463.55
Storage condition -20℃
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