F7H

Names

[ Name ]:
F7H

Biological Activity

[Description]:

F7H is a Frizzled receptor FZD7 antagonist (IC50: 1.25 μM). Frizzled receptors (FZDs) influence Wnt signaling, mediating embryonic development and tissue homeostasis. F7H is a potent ligand for the FZD7 transmembrane domain (TMD)[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Stem Cell/Wnt >> Wnt

[Target]

IC50: 1.25 μM (Frizzled receptor, FZD7)[1]

[References]

[1]. Li C, et al. Structure-Based Ligand Discovery Targeting the Transmembrane Domain of Frizzled Receptor FZD7. J Med Chem. 2023 Sep 14;66(17):11855-11868.. .

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₄H₁₈FN₃O₂S₂

[ Molecular Weight ]:
463.55

[ Storage condition ]:
-20℃

Related Compounds

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