A55453

Modify Date: 2025-09-18 11:53:31

A55453 Structure
A55453 structure
Common Name A55453
CAS Number 89687-06-9 Molecular Weight 464.56000
Density 1.264g/cm3 Boiling Point 752.7ºC at 760 mmHg
Molecular Formula C25H32N6O3 Melting Point N/A
MSDS N/A Flash Point 409ºC

 Use of A55453


A55453 is a prazosin analogue and a potent α1-adrenergic antagonist. 125I-A55453 is a high-affinity alpha 1-adrenergic receptor probe[1].

 Names

Name 1-[4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-5-(4-aminophenyl)pentan-1-one

 A55453 Biological Activity

Description A55453 is a prazosin analogue and a potent α1-adrenergic antagonist. 125I-A55453 is a high-affinity alpha 1-adrenergic receptor probe[1].
Related Catalog
References

[1]. Dickinson KE, et al. Photoaffinity cross-linking of a radioiodinated probe, 125I-A55453, into alpha 1-adrenergic receptors. Mol Pharmacol. 1984;26(2):187-195.

 Chemical & Physical Properties

Density 1.264g/cm3
Boiling Point 752.7ºC at 760 mmHg
Molecular Formula C25H32N6O3
Molecular Weight 464.56000
Flash Point 409ºC
Exact Mass 464.25400
PSA 120.56000
LogP 3.38720
Index of Refraction 1.646
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