Imiquimod maleate

Modify Date: 2024-01-11 16:11:02

Imiquimod maleate Structure
Imiquimod maleate structure
Common Name Imiquimod maleate
CAS Number 896106-16-4 Molecular Weight 356.376
Density N/A Boiling Point N/A
Molecular Formula C18H20N4O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Imiquimod maleate


Imiquimod maleate is an immune response modifier that acts as a toll-like receptor 7agonist.

 Names

Name Imiquimod maleate
Synonym More Synonyms

 Imiquimod maleate Biological Activity

Description Imiquimod maleate is an immune response modifier that acts as a toll-like receptor 7agonist.
Related Catalog
Target

Toll-like receptor 7

In Vivo In animal models, imiquimod stimulates the innate immune response by increasing NK cell activity, activating macrophages to secretecytokines and nitric oxide, and inducing proliferation and differentiation of B lymphocytes. Imiquimod stimulates the innate immune response through induction, synthesis, and release of cytokines, including interferon-a (IFN-α), interleukin (IL)-6, and tumour necrosis factor (TNF)-α[1].
References

[1]. Bilu D, et al. Imiquimod: modes of action. Br J Dermatol. 2003 Nov;149 Suppl 66:5-8.

 Chemical & Physical Properties

Molecular Formula C18H20N4O4
Molecular Weight 356.376
Exact Mass 356.148468
Storage condition 2-8℃

 Synonyms

1H-Imidazo[4,5-c]quinolin-4-amine, 1-(2-methylpropyl)-, (2Z)-2-butenedioate (1:1)
1-Isobutyl-1H-imidazo[4,5-c]quinolin-4-amine (2Z)-2-butenedioate (1:1)
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