Imiquimod (hydrochloride)

Modify Date: 2024-01-11 20:57:37

Imiquimod (hydrochloride) Structure
Imiquimod (hydrochloride) structure
Common Name Imiquimod (hydrochloride)
CAS Number 99011-78-6 Molecular Weight 276.76500
Density N/A Boiling Point N/A
Molecular Formula C14H17ClN4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Imiquimod (hydrochloride)


Imiquimod hydrochloride is an immune response modifier that acts as a toll-like receptor 7agonist.

 Names

Name 1H-Imidazo[4,5-c]quinolin-4-amine, 1-(2-methylpropyl)-, hydrochloride
Synonym More Synonyms

 Imiquimod (hydrochloride) Biological Activity

Description Imiquimod hydrochloride is an immune response modifier that acts as a toll-like receptor 7agonist.
Related Catalog
Target

Toll-like receptor 7

In Vivo In animal models, imiquimod stimulates the innate immune response by increasing NK cell activity, activating macrophages to secretecytokines and nitric oxide, and inducing proliferation and differentiation of B lymphocytes. Imiquimod stimulates the innate immune response through induction, synthesis, and release of cytokines, including interferon-a (IFN-α), interleukin (IL)-6, and tumour necrosis factor (TNF)-α[1].
References

[1]. Bilu D, et al. Imiquimod: modes of action. Br J Dermatol. 2003 Nov;149 Suppl 66:5-8.

 Chemical & Physical Properties

Molecular Formula C14H17ClN4
Molecular Weight 276.76500
Exact Mass 276.11400
PSA 56.73000
LogP 4.20590

 Synonyms

Imiquimod (hydrochloride)
1H-Imidazo[4,5-c]quinolin-4-amine, 1-(2-methylpropyl)-, monohydrochloride
Imiquimod hydrochloride
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