Hydroxy-PEG1-acid

Modify Date: 2024-01-14 18:13:28

Hydroxy-PEG1-acid Structure
Hydroxy-PEG1-acid structure
Common Name Hydroxy-PEG1-acid
CAS Number 89211-34-7 Molecular Weight 134.13000
Density N/A Boiling Point N/A
Molecular Formula C5H10O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Hydroxy-PEG1-acid


Hydroxy-PEG1-acid is a non-cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

 Names

Name 3-(2-hydroxyethoxy)propionic acid
Synonym More Synonyms

 Hydroxy-PEG1-acid Biological Activity

Description Hydroxy-PEG1-acid is a non-cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog
Target

Non-cleavable

In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
References

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

 Chemical & Physical Properties

Molecular Formula C5H10O4
Molecular Weight 134.13000
Exact Mass 134.05800
PSA 66.76000

 Synonyms

3-(2-Hydroxy-ethoxy)-propionsaeure
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