Verdiperstat

Modify Date: 2025-08-25 10:22:13

Verdiperstat Structure
Verdiperstat structure
Common Name Verdiperstat
CAS Number 890655-80-8 Molecular Weight 253.32
Density N/A Boiling Point N/A
Molecular Formula C11H15N3O2S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Verdiperstat


Verdiperstat (AZD3241) is a selective, irreversible and orally active myeloperoxidase inhibitor, with an IC50 of 630 nM, and can be used in the research of neurodegenerative brain disorders.

 Names

Name Verdiperstat
Synonym More Synonyms

 Verdiperstat Biological Activity

Description Verdiperstat (AZD3241) is a selective, irreversible and orally active myeloperoxidase inhibitor, with an IC50 of 630 nM, and can be used in the research of neurodegenerative brain disorders.
Related Catalog
Target

IC50: 630 nM (Myeloperoxidase)[1]

In Vitro Verdiperstat (AZD3241) is a myeloperoxidase (MPO) inhibitor, with an IC50 of 630 nM, and is used in the research of neurodegenerative brain disorders[1]. Verdiperstat (AZD3241) selectively and irreversibly inhibits myeloperoxidase, and may involves reduction of oxidative stress leading to reduction of sustained neuroinflammation[2].
References

[1]. Johnström P, et al. Development of rapid multistep carbon-11 radiosynthesis of the myeloperoxidase inhibitor AZD3241 to assess brain exposure by PET microdosing. Nucl Med Biol. 2015 Jun;42(6):555-60.

[2]. Jucaite A, et al. Effect of the myeloperoxidase inhibitor AZD3241 on microglia: a PET study in Parkinson's disease. Brain. 2015 Sep;138(Pt 9):2687-700.

 Chemical & Physical Properties

Molecular Formula C11H15N3O2S
Molecular Weight 253.32
Storage condition -20℃

 Synonyms

MFCD30533444
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.
Top Suppliers:I want be here



Get all suppliers and price by the below link:

Verdiperstat suppliers


Price: ¥3850/10 mM * 1 mL in DMSO

Reference only. check more Verdiperstat price