Acid-PEG2-ethyl propionate

Modify Date: 2025-08-25 08:14:46

Acid-PEG2-ethyl propionate Structure
Acid-PEG2-ethyl propionate structure
Common Name Acid-PEG2-ethyl propionate
CAS Number 886362-90-9 Molecular Weight 234.24600
Density 1.145g/cm3 Boiling Point 370.8ºC at 760 mmHg
Molecular Formula C10H18O6 Melting Point N/A
MSDS N/A Flash Point 139.5ºC

 Use of Acid-PEG2-ethyl propionate


Acid-PEG2-ethyl propionate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 3-(2-(3-Ethoxy-3-oxopropoxy)ethoxy)propanoic acid
Synonym More Synonyms

 Acid-PEG2-ethyl propionate Biological Activity

Description Acid-PEG2-ethyl propionate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Density 1.145g/cm3
Boiling Point 370.8ºC at 760 mmHg
Molecular Formula C10H18O6
Molecular Weight 234.24600
Flash Point 139.5ºC
Exact Mass 234.11000
PSA 82.06000
LogP 0.44750
Index of Refraction 1.452
InChIKey KEGUKRRJONEXNN-UHFFFAOYSA-N
SMILES CCOC(=O)CCOCCOCCC(=O)O

 Safety Information

Hazard Codes Xi
HS Code 2918990090

 Customs

HS Code 2918990090
Summary 2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Synonyms

3-[2-(3-ethoxy-3-oxopropoxy)ethoxy]propanoic acid
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