4-Iodo-1H-indazole

Modify Date: 2024-01-09 20:24:45

4-Iodo-1H-indazole Structure
4-Iodo-1H-indazole structure
Common Name 4-Iodo-1H-indazole
CAS Number 885522-11-2 Molecular Weight 244.033
Density 2.1±0.1 g/cm3 Boiling Point 358.2±15.0 °C at 760 mmHg
Molecular Formula C7H5IN2 Melting Point N/A
MSDS Chinese USA Flash Point 170.4±20.4 °C
Symbol GHS07
GHS07
Signal Word Warning

 Names

Name 4-Iodo-1H-indazole
Synonym More Synonyms

 Chemical & Physical Properties

Density 2.1±0.1 g/cm3
Boiling Point 358.2±15.0 °C at 760 mmHg
Molecular Formula C7H5IN2
Molecular Weight 244.033
Flash Point 170.4±20.4 °C
Exact Mass 243.949738
PSA 28.68000
LogP 2.85
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.788

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302-H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
RIDADR NONH for all modes of transport

 Synthetic Route

~25%

4-Iodo-1H-indazole Structure

4-Iodo-1H-indazole

CAS#:885522-11-2

Literature: GENENTECH, INC.; F. HOFFMANN-LA ROCHE AG Patent: WO2009/146406 A1, 2009 ; Location in patent: Page/Page column 68 ; WO 2009/146406 A1

~32%

4-Iodo-1H-indazole Structure

4-Iodo-1H-indazole

CAS#:885522-11-2

Literature: Dai, Yujia; Hartandi, Kresna; Ji, Zhiqin; Ahmed, Asma A.; Albert, Daniel H.; Bauch, Joy L.; Bouska, Jennifer J.; Bousquet, Peter F.; Cunha, George A.; Glaser, Keith B.; Harris, Christopher M.; Hickman, Dean; Guo, Jun; Li, Junling; Marcotte, Patrick A.; Marsh, Kennan C.; Moskey, Maria D.; Martin, Ruth L.; Olson, Amanda M.; Osterling, Donald J.; Pease, Lori J.; Soni, Niru B.; Stewart, Kent D.; Stoll, Vincent S.; Tapang, Paul; Reuter, David R.; Davidsen, Steven K.; Michaelides, Michael R. Journal of Medicinal Chemistry, 2007 , vol. 50, # 7 p. 1584 - 1597

~%

4-Iodo-1H-indazole Structure

4-Iodo-1H-indazole

CAS#:885522-11-2

Literature: WO2012/82997 A1, ; WO 2012/082997 A1

~%

4-Iodo-1H-indazole Structure

4-Iodo-1H-indazole

CAS#:885522-11-2

Literature: WO2012/82997 A1, ; WO 2012/082997 A1

 Synonyms

4-Iodo-1H-indazole
1H-Indazole, 4-iodo-