R-360163
Modify Date: 2025-08-25 12:39:01
R-360163 structure
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Common Name | R-360163 | ||
|---|---|---|---|---|
| CAS Number | 883791-50-2 | Molecular Weight | 392.365 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C20H16N4O5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of R-360163R-360163 is a small molecule inhibitor that effectively inhibits the β-catenin/Tcf4 interaction with Ki of 16 uM in FP assay; displays 16-fold and 25-fold selectivity over β-catenin/E-cadherin and β-catenin/APC interactions, respectively. |
| Name | MFCD00614570 |
|---|---|
| Synonym | More Synonyms |
| Description | R-360163 is a small molecule inhibitor that effectively inhibits the β-catenin/Tcf4 interaction with Ki of 16 uM in FP assay; displays 16-fold and 25-fold selectivity over β-catenin/E-cadherin and β-catenin/APC interactions, respectively. |
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| References | References 1. Zhang M, et al. ACS Med Chem Lett. 2013 Jan 8;4(2):306-11. View Related Products by Target Beta-catenin |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Molecular Formula | C20H16N4O5 |
| Molecular Weight | 392.365 |
| Exact Mass | 392.112061 |
| LogP | 2.62 |
| Index of Refraction | 1.669 |
| InChIKey | HARXMVZWZSAPPL-UHFFFAOYSA-N |
| SMILES | C=CCn1c(O)c(N=NC(=O)C(=O)Nc2cccc(C(=O)O)c2)c2ccccc21 |
| Benzoic acid, 3-[[2-[(2Z)-2-[1,2-dihydro-2-oxo-1-(2-propen-1-yl)-3H-indol-3-ylidene]hydrazinyl]-1,2-dioxoethyl]amino]- |
| 3-({[(2Z)-2-(1-Allyl-2-oxo-1,2-dihydro-3H-indol-3-ylidene)hydrazino](oxo)acetyl}amino)benzoic acid |
| MFCD00614570 |