Eupalinolide B

Modify Date: 2025-08-24 05:42:55

Eupalinolide B structure	Common Name	Eupalinolide B
	CAS Number	877822-40-7	Molecular Weight	462.490
	Density	1.24±0.1 g/cm3 (20 ºC 760 Torr)	Boiling Point	618.6±55.0 °C at 760 mmHg
	Molecular Formula	C₂₄H₃₀O₉	Melting Point	N/A
	MSDS	N/A	Flash Point	205.4±25.0 °C

Use of Eupalinolide B

Eupalinolide A, isolated from Eupatorium lindleyanum, induces the expression of HSP70 via the activation of HSF1 by inhibiting the interaction between HSF1 and HSP90[1].

Name	2-Butenoic acid, 4-hydroxy-2-methyl-, (3aR,4R,6Z,9S,10Z,11aR)-9-(acetyloxy)-6-[(acetyloxy)methyl]-2,3,3a,4,5,8,9,11a-octahydro-10-methyl-3-methylene-2-oxocyclodeca[b]furan-4-yl ester, (2E)
Synonym	More Synonyms

Description	Eupalinolide A, isolated from Eupatorium lindleyanum, induces the expression of HSP70 via the activation of HSF1 by inhibiting the interaction between HSF1 and HSP90[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> HSP Research Areas >> Inflammation/Immunology Signaling Pathways >> Cell Cycle/DNA Damage >> HSP
Target	HSF1
References	[1]. Yamashita Y, et al. Purification and characterization of HSP-inducers from Eupatorium lindleyanum. Biochem Pharmacol. 2012;83(7):909-922.

Density	1.24±0.1 g/cm3 (20 ºC 760 Torr)
Boiling Point	618.6±55.0 °C at 760 mmHg
Molecular Formula	C₂₄H₃₀O₉
Molecular Weight	462.490
Flash Point	205.4±25.0 °C
Exact Mass	462.188995
PSA	125.43000
LogP	2.50
Vapour Pressure	0.0±4.1 mmHg at 25°C
Index of Refraction	1.541
InChIKey	HPWMABTYJYZFLK-JRRMTSHWSA-N
SMILES	C=C1C(=O)OC2C=C(C)C(OC(C)=O)CC=C(COC(C)=O)CC(OC(=O)C(C)=CCO)C12
Storage condition	2-8°C

2-Butenoic acid, 4-hydroxy-2-methyl-, (3aR,4R,6E,9S,10Z,11aR)-9-(acetyloxy)-6-[(acetyloxy)methyl]-2,3,3a,4,5,8,9,11a-octahydro-10-methyl-3-methylene-2-oxocyclodeca[b]furan-4-yl ester, (2E)-

Eupalinolide B

Eupalinolide A

(3aR,4R,6E,9S,10Z,11aR)-9-Acetoxy-6-(acetoxymethyl)-10-methyl-3-methylene-2-oxo-2,3,3a,4,5,8,9,11a-octahydrocyclodeca[b]furan-4-yl (2E)-4-hydroxy-2-methyl-2-butenoate

Eupalinolide G

EupalinolideB

Eupalinolide-B