LM985

Modify Date: 2024-01-22 18:29:14

LM985 structure	Common Name	LM985
	CAS Number	87626-56-0	Molecular Weight	379.44900
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₃H₂₅NO₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of LM985

LM985 is one of a series of compounds based on the flavone ring structure, with anti-tumor activities.

Name	2-(diethylamino)ethyl 2-(4-oxo-2-phenylchromen-8-yl)acetate
Synonym	More Synonyms

Description	LM985 is one of a series of compounds based on the flavone ring structure, with anti-tumor activities.
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Cancer
In Vitro	LM985 shows inhibitory effects against MAC 13 cells, but MAC 15A cells are less sensitive to LM985[1].
In Vivo	LM985 (200 mg/kg, s.c.) shows moderate activity against MAC 13, and after repeated injection 7 days, responses are considerably enhanced[2].
References	[1]. M. C. Bibby, et al. Factors involved in the anti-cancer activity of the investigational agents LM985 (flavone acetic acid ester) and LM975 (flavone acetic acid). Br J Cancer. 1987 Feb; 55(2): 159-163. [2]. J. A. Double, et al. Pharmacokinetics and anti-tumour activity of LM985 in mice bearing transplantable adenocarcinomas of the colon. Br J Cancer. 1986 Oct; 54(4): 595-600.

Molecular Formula	C₂₃H₂₅NO₄
Molecular Weight	379.44900
Exact Mass	379.17800
PSA	59.75000
LogP	3.88750
Storage condition	2-8℃

lm 985

LM985

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