Safracin B

Modify Date: 2025-08-27 02:59:31

$Safracin B Structure$ Safracin B structure	Common Name	Safracin B
	CAS Number	87578-99-2	Molecular Weight	540.60800
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₈H₃₆N₄O₇	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Safracin B

Safracin B, a tetrahydroisoquinoline (THIQ) alkaloid, is a naturally occurring antibiotic from Pseudomonas fluorescens. Safracin B exhibits broad spectrum antimicrobial and strong antitumor activities[1].

Name	Safracin B

Description	Safracin B, a tetrahydroisoquinoline (THIQ) alkaloid, is a naturally occurring antibiotic from Pseudomonas fluorescens. Safracin B exhibits broad spectrum antimicrobial and strong antitumor activities[1].
Related Catalog	Research Areas >> Cancer Research Areas >> Infection
In Vivo	Safracin B (0.005-5 mg/kg/day; for 9 days) prolongs the life span of tumor-bearing mice and shows antitumor activity against L1210 and P388 leukemias and B16 melanoma in Female BALB/c x DBA/2 F1 (CD2F1) mice weighing 19-24 g[2]. The LD50 is 7.3 mg/kg with safracin B in normal CD2F1 mice by ip administration[2].
References	[1]. Gong-Li Tang, et al.Biosynthesis of Tetrahydroisoquinoline Antibiotics. Curr Top Med Chem. 2016;16(15):1717-26. [2]. T Okumoto, et al. Activity of Safracins A and B, Heterocyclic Quinone Antibiotics, on Experimental Tumors in Mice. J Antibiot (Tokyo). 1985 Jun;38(6):767-71.

Molecular Formula	C₂₈H₃₆N₄O₇
Molecular Weight	540.60800
Exact Mass	540.25800
PSA	154.66000
LogP	1.18090

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TX1404550

CHEMICAL NAME :: Propanamide, 2-amino-N-((6,7,9,10,13,14,14a,15-octahydro-1,7-dihyd roxy-2,11-dimethoxy- 3,12,16-trimethyl-10,13-dioxo-6,15-imino-5H-isoquino( 3,2-b)(3)benzazocin-9 -yl)methyl)-

CAS REGISTRY NUMBER :: 87578-99-2

LAST UPDATED :: 199401

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C28-H36-N4-O7

MOLECULAR WEIGHT :: 540.68

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 3540 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JKXXAF Japanese Kokai Tokyo Koho Patents. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #83-113192

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Palmitic acid
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Purity: 98.0%
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Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: SAFRACIN B
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
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Contact: Ms Wang
Email: enquiry@dycnchem.com

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.