3'-Hydroxy Repaglinide

Modify Date: 2025-08-22 16:40:34

3'-Hydroxy Repaglinide Structure
3'-Hydroxy Repaglinide structure
 Common Name 3'-Hydroxy Repaglinide
CAS Number 874908-14-2 Molecular Weight 468.58500
Density 1.186g/cm3 Boiling Point 709.6ºC at 760 mmHg
Molecular Formula C27H36N2O5 Melting Point 79-82ºC
MSDS N/A Flash Point 383ºC

 Use of 3'-Hydroxy Repaglinide


3'-Hydroxy Repaglinide is a main CYP2C8 metabolite of Repaglinide. Repaglinide is a carbamoylmethyl benzoic acid (CMBA) derivative, which recently has become available for the treatment of type II diabetes[1][2].

 Names

Name 2-ethoxy-4-[2-[[1-[2-(3-hydroxypiperidin-1-yl)phenyl]-3-methylbutyl]amino]-2-oxoethyl]benzoic acid

 3'-Hydroxy Repaglinide Biological Activity

Description 3'-Hydroxy Repaglinide is a main CYP2C8 metabolite of Repaglinide. Repaglinide is a carbamoylmethyl benzoic acid (CMBA) derivative, which recently has become available for the treatment of type II diabetes[1][2].
Related Catalog
References

[1]. A liquid chromatography-tandem mass spectrometry analysis of nine cytochrome P450 probedrugs and their corresponding metabolites in human serum and urine. Anal Bioanal Chem. 2017 Jan;409(1):251-268.

[2]. Honkalammi J, et al. Mechanism-based inactivation of CYP2C8 by gemfibrozil occurs rapidly in humans. Clin Pharmacol Ther. 2011 Apr;89(4):579-86.

 Chemical & Physical Properties

Density 1.186g/cm3
Boiling Point 709.6ºC at 760 mmHg
Melting Point 79-82ºC
Molecular Formula C27H36N2O5
Molecular Weight 468.58500
Flash Point 383ºC
Exact Mass 468.26200
PSA 102.59000
LogP 5.09600
Index of Refraction 1.581
Storage condition -20°C
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Chemsrc provides 3'-Hydroxy Repaglinide(CAS#:874908-14-2) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of 3'-Hydroxy Repaglinide are included as well.>> amp version: 3'-Hydroxy Repaglinide

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