S29434
Modify Date: 2025-08-25 09:32:07
S29434 structure
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Common Name | S29434 | ||
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| CAS Number | 874484-20-5 | Molecular Weight | 374.39 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C21H18N4O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of S29434S29434 (NMDPEF) is a potent, competitive, selective and cell-permeable inhibitor of quinone reductase 2 (QR2), with IC50s ranging from 5 to 16 nM for human QR2 at different organizational levels, and has good selectivity for QR2 over QR1. S29434 (NMDPEF) induces autophagy and inhibits QR2-mediated ROS production[1]. |
| Name | S29434 |
|---|
| Description | S29434 (NMDPEF) is a potent, competitive, selective and cell-permeable inhibitor of quinone reductase 2 (QR2), with IC50s ranging from 5 to 16 nM for human QR2 at different organizational levels, and has good selectivity for QR2 over QR1. S29434 (NMDPEF) induces autophagy and inhibits QR2-mediated ROS production[1]. |
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| Related Catalog | |
| Target |
IC50: 5 nM (h QR2, expressed in E. coli, NRH as co-substrate), 16 nM (h QR2, expressed in E. coli, with BNAH as co-substrate)[1] |
| References |
| Molecular Formula | C21H18N4O3 |
|---|---|
| Molecular Weight | 374.39 |
| InChIKey | XJIUMLVQBQKCJA-UHFFFAOYSA-N |
| SMILES | COc1ccc2c(n1)c(CCNC(=O)c1ccco1)c1n2Cc2cccnc2-1 |