Thiocolchicine analog
Modify Date: 2025-08-26 12:33:31
Thiocolchicine analog structure
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Common Name | Thiocolchicine analog | ||
|---|---|---|---|---|
| CAS Number | 87424-26-8 | Molecular Weight | 401.47600 | |
| Density | 1.33g/cm3 | Boiling Point | 766.8ºC at 760 mmHg | |
| Molecular Formula | C21H23NO5S | Melting Point | 218-220ºC | |
| MSDS | N/A | Flash Point | 417.6ºC | |
| Name | N-[(7S)-2-hydroxy-1,3-dimethoxy-10-methylsulfanyl-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide |
|---|---|
| Synonym | More Synonyms |
| Density | 1.33g/cm3 |
|---|---|
| Boiling Point | 766.8ºC at 760 mmHg |
| Melting Point | 218-220ºC |
| Molecular Formula | C21H23NO5S |
| Molecular Weight | 401.47600 |
| Flash Point | 417.6ºC |
| Exact Mass | 401.13000 |
| PSA | 110.16000 |
| LogP | 3.67280 |
| Index of Refraction | 1.636 |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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~3%
Thiocolchicine ... CAS#:87424-26-8 |
| Literature: Guan, Jian; Brossi, Arnold; Zhu, Xiao-Kang; Wang, Hui-Kang; Lee, Kuo-Hsiung Synthetic Communications, 1998 , vol. 28, # 9 p. 1585 - 1591 |
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~%
Thiocolchicine ... CAS#:87424-26-8 |
| Literature: Nakagawa-Goto, Kyoko; Chen, Cyril X.; Hamel, Ernest; Wu, Chin-Chung; Bastow, Kenneth F.; Brossi, Arnold; Lee, Kuo-Hsiung Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 1 p. 235 - 238 |
| Precursor 3 | |
|---|---|
| DownStream 0 | |
| N-((S)-2-hydroxy-1,3-dimethoxy-10-methylsulfanyl-9-oxo-5,6,7,9-tetrahydro-benzo[a]heptalen-7-yl)-acetamide |
| N-((S)-2-Hydroxy-1,3-dimethoxy-10-methylmercapto-9-oxo-5,6,7,9-tetrahydro-benzo[a]heptalen-7-yl)-acetamid |
| 2-Demethyl Thiocolchicine |
| COLCHICINE,O(sup 2)-DEMETHYL-10-THIO |
| (S)-7-Acetylamino-2-hydroxy-1,3-dimethoxy-10-methylmercapto-6,7-dihydro-5H-benzo[a]heptalen-9-on |
| O(sup 2)-Demethyl-10-thiocolchicine |