(-)-Denudatin B

Modify Date: 2025-08-27 16:57:54

(-)-Denudatin B Structure
(-)-Denudatin B structure
Common Name (-)-Denudatin B
CAS Number 87402-88-8 Molecular Weight 356.41
Density 1.2±0.1 g/cm3 Boiling Point 491.1±45.0 °C at 760 mmHg
Molecular Formula C21H24O5 Melting Point N/A
MSDS N/A Flash Point 214.2±28.8 °C

 Use of (-)-Denudatin B


(-)-Denudatin B is an antiplatelet agent. (-)-Denudatin B relaxed vascular smooth muscle by inhibiting the Ca2+ influx through voltage-gated and receptor-operated Ca2+ channels[1]. And (-)-Denudatin B has nonspecific antiplatelet action

 Names

Name Denudatin B
Synonym More Synonyms

 (-)-Denudatin B Biological Activity

Description (-)-Denudatin B is an antiplatelet agent. (-)-Denudatin B relaxed vascular smooth muscle by inhibiting the Ca2+ influx through voltage-gated and receptor-operated Ca2+ channels[1]. And (-)-Denudatin B has nonspecific antiplatelet action
Related Catalog
References

[1]. Yu SM,et al. Vasorelaxing effect in rat thoracic aorta caused by denudatin B, isolated from the Chinese herb, magnolia fargesii. Eur J Pharmacol. 1990;187(1):39-47.

[2]. Teng CM, et al. Inhibition of thrombin- and collagen-induced phosphoinositides breakdown in rabbit platelets by a PAF antagonist--denudatin B, an isomer of kadsurenone. Thromb Res. 1990;59(1):121-130.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 491.1±45.0 °C at 760 mmHg
Molecular Formula C21H24O5
Molecular Weight 356.41
Flash Point 214.2±28.8 °C
Exact Mass 356.162384
PSA 53.99000
LogP 2.87
Vapour Pressure 0.0±1.2 mmHg at 25°C
Index of Refraction 1.565
InChIKey VDYACOATPFOZIO-HBUDHLSFSA-N
SMILES C=CCC1=CC2(OC)C(=CC1=O)OC(c1ccc(OC)c(OC)c1)C2C

 Safety Information

Hazard Codes Xi

 Synonyms

(2S,3R,3aR)-5-Allyl-2-(3,4-dimethoxyphenyl)-3a-methoxy-3-methyl-3,3a-dihydro-1-benzofuran-6(2H)-one
Denudatin B
6(2H)-Benzofuranone, 2-(3,4-dimethoxyphenyl)-3,3a-dihydro-3a-methoxy-3-methyl-5-(2-propen-1-yl)-, (2S,3R,3aR)-
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