PI3Kδ-IN-15
Modify Date: 2025-09-18 19:47:11
PI3Kδ-IN-15 structure
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Common Name | PI3Kδ-IN-15 | ||
|---|---|---|---|---|
| CAS Number | 870281-17-7 | Molecular Weight | 401.40 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C21H16FN7O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of PI3Kδ-IN-15PI3Kδ-IN-15 (compound 6b) is a selective PI3Kδ inhibitor with an IC50 of 0.5 nM for p110δ. PI3Kδ-IN-15 inhibits PI3Kδ with >30-fold higher potency than PI3Kγ, PI3Kβ, and PI3Kα[1]. |
| Name | 5-Fluoro-3-phenyl-2-[(1S)-1-(9H-purin-6-ylamino)ethyl]-4(3H)-quinazolinone |
|---|---|
| Synonym | More Synonyms |
| Description | PI3Kδ-IN-15 (compound 6b) is a selective PI3Kδ inhibitor with an IC50 of 0.5 nM for p110δ. PI3Kδ-IN-15 inhibits PI3Kδ with >30-fold higher potency than PI3Kγ, PI3Kβ, and PI3Kα[1]. |
|---|---|
| Related Catalog | |
| Target |
p110δ:0.5 nM (IC50) p110γ:15.3 nM (IC50) p110β:145 nM (IC50) p110α:152 nM (IC50) |
| References |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Molecular Formula | C21H16FN7O |
| Molecular Weight | 401.40 |
| Exact Mass | 401.140045 |
| LogP | 2.43 |
| Index of Refraction | 1.759 |
| 4(3H)-Quinazolinone, 5-fluoro-3-phenyl-2-[(1S)-1-(9H-purin-6-ylamino)ethyl]- |
| 5-Fluoro-3-phenyl-2-[(1S)-1-(9H-purin-6-ylamino)ethyl]-4(3H)-quinazolinone |