T-26c
Modify Date: 2025-08-25 08:32:41
T-26c structure
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Common Name | T-26c | ||
|---|---|---|---|---|
| CAS Number | 869296-13-9 | Molecular Weight | 479.51 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C24H21N3O6S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of T-26cT-26c is highly potent and selective matrix metalloproteinase-13 (MMP-13) inhibitor with an IC50 of 6.75 pM and more than 2600-fold selectivity over the other related metalloenzymes[1]. |
| Name | T-26c |
|---|---|
| Synonym | More Synonyms |
| Description | T-26c is highly potent and selective matrix metalloproteinase-13 (MMP-13) inhibitor with an IC50 of 6.75 pM and more than 2600-fold selectivity over the other related metalloenzymes[1]. |
|---|---|
| Related Catalog | |
| Target |
IC50: 6.75 pM (MMP-13)[1] |
| In Vitro | T-26c significantly inhibits the breakdown of collagen (87.4% inhibition at 0.1 μM) in IL-1β and oncostatin M stimulated cartilage[1]. |
| References |
| Molecular Formula | C24H21N3O6S |
|---|---|
| Molecular Weight | 479.51 |
| InChIKey | CDQRIIUMNLMHRH-UHFFFAOYSA-N |
| SMILES | COc1cccc(CNC(=O)c2nc3scc(COCc4ccc(C(=O)O)cc4)c3c(=O)[nH]2)c1 |
| CPD1612 |