869296-13-9
869296-13-9 structure
- Name: T-26c
- Chemical Name: T-26c
- CAS Number: 869296-13-9
- Molecular Formula: C24H21N3O6S
- Molecular Weight: 479.51
- Catalog: Research Areas Inflammation/Immunology
- Create Date: 2018-06-22 06:47:10
- Modify Date: 2024-01-09 16:41:38
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T-26c is highly potent and selective matrix metalloproteinase-13 (MMP-13) inhibitor with an IC50 of 6.75 pM and more than 2600-fold selectivity over the other related metalloenzymes[1].
| Name | T-26c |
|---|---|
| Synonyms | CPD1612 |
| Description | T-26c is highly potent and selective matrix metalloproteinase-13 (MMP-13) inhibitor with an IC50 of 6.75 pM and more than 2600-fold selectivity over the other related metalloenzymes[1]. |
|---|---|
| Related Catalog | |
| Target |
IC50: 6.75 pM (MMP-13)[1] |
| In Vitro | T-26c significantly inhibits the breakdown of collagen (87.4% inhibition at 0.1 μM) in IL-1β and oncostatin M stimulated cartilage[1]. |
| References |
| Molecular Formula | C24H21N3O6S |
|---|---|
| Molecular Weight | 479.51 |