N-[(2S)-2-(Glycoloylamino)-4-phenylbutanoyl]-L-leucyl-N-{(2S)-4-methyl-1-[(2R)-2-methyl-2-oxiranyl]-1-oxo-2-pentanyl}-L-phenylalaninamide

Modify Date: 2024-04-07 19:34:18

N-[(2S)-2-(Glycoloylamino)-4-phenylbutanoyl]-L-leucyl-N-{(2S)-4-methyl-1-[(2R)-2-methyl-2-oxiranyl]-1-oxo-2-pentanyl}-L-phenylalaninamide Structure
N-[(2S)-2-(Glycoloylamino)-4-phenylbutanoyl]-L-leucyl-N-{(2S)-4-methyl-1-[(2R)-2-methyl-2-oxiranyl]-1-oxo-2-pentanyl}-L-phenylalaninamide structure
Common Name N-[(2S)-2-(Glycoloylamino)-4-phenylbutanoyl]-L-leucyl-N-{(2S)-4-methyl-1-[(2R)-2-methyl-2-oxiranyl]-1-oxo-2-pentanyl}-L-phenylalaninamide
CAS Number 868540-02-7 Molecular Weight 650.80
Density 1.177±0.06 g/cm3(Predicted) Boiling Point 953.7±65.0 °C(Predicted)
Molecular Formula C36H50N4O7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of N-[(2S)-2-(Glycoloylamino)-4-phenylbutanoyl]-L-leucyl-N-{(2S)-4-methyl-1-[(2R)-2-methyl-2-oxiranyl]-1-oxo-2-pentanyl}-L-phenylalaninamide


Enzyme-IN-1 (compound 1) is a peptide-based inhibitor of N-terminal nucleophile (Ntn) hydrolases. Specifically, Enzyme-IN-1 inhibits the chymotrypsin-like activity (CT-L) of the 20S proteasome. Enzyme-IN-1 may has potential antiinflammatory properties[1].

 Names

Name Enzyme-IN-1

  Biological Activity

Description Enzyme-IN-1 (compound 1) is a peptide-based inhibitor of N-terminal nucleophile (Ntn) hydrolases. Specifically, Enzyme-IN-1 inhibits the chymotrypsin-like activity (CT-L) of the 20S proteasome. Enzyme-IN-1 may has potential antiinflammatory properties[1].
Related Catalog
References

[1]. Smyth Mark, et al. Preparation of peptides for the inhibition of enzymes. United States, US20050245435 A1. 2005-11-03.

 Chemical & Physical Properties

Density 1.177±0.06 g/cm3(Predicted)
Boiling Point 953.7±65.0 °C(Predicted)
Molecular Formula C36H50N4O7
Molecular Weight 650.80
Storage condition 2-8°C
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