868540-02-7

868540-02-7 structure

Name: N-[(2S)-2-(Glycoloylamino)-4-phenylbutanoyl]-L-leucyl-N-{(2S)-4-methyl-1-[(2R)-2-methyl-2-oxiranyl]-1-oxo-2-pentanyl}-L-phenylalaninamide
Chemical Name: Enzyme-IN-1
CAS Number: 868540-02-7
Molecular Formula: C₃₆H₅₀N₄O₇
Molecular Weight: 650.80
Catalog: Signaling Pathways Metabolic Enzyme/Protease Proteasome
Create Date: 2023-05-11 13:21:49
Modify Date: 2025-09-21 11:25:17
Enzyme-IN-1 (compound 1) is a peptide-based inhibitor of N-terminal nucleophile (Ntn) hydrolases. Specifically, Enzyme-IN-1 inhibits the chymotrypsin-like activity (CT-L) of the 20S proteasome. Enzyme-IN-1 may has potential antiinflammatory properties[1].

Name	Enzyme-IN-1

Description	Enzyme-IN-1 (compound 1) is a peptide-based inhibitor of N-terminal nucleophile (Ntn) hydrolases. Specifically, Enzyme-IN-1 inhibits the chymotrypsin-like activity (CT-L) of the 20S proteasome. Enzyme-IN-1 may has potential antiinflammatory properties[1].
Related Catalog	Research Areas >> Inflammation/Immunology Signaling Pathways >> Metabolic Enzyme/Protease >> Proteasome
References	[1]. Smyth Mark, et al. Preparation of peptides for the inhibition of enzymes. United States, US20050245435 A1. 2005-11-03.