4-oxo-4-HPR

Modify Date: 2023-01-15 09:32:32

4-oxo-4-HPR structure	Common Name	4-oxo-4-HPR
	CAS Number	865536-65-8	Molecular Weight	405.53
	Density	1.131g/cm3	Boiling Point	641.8ºC at 760 mmHg
	Molecular Formula	C₂₆H₃₁NO₃	Melting Point	N/A
	MSDS	N/A	Flash Point	341.9ºC

Use of 4-oxo-4-HPR

4-Oxofenretinide (4-Oxo-4-HPR) is a metabolite of Fenretinide (HY-15373). 4-Oxofenretinide induces cell growth inhibition in ovarian, breast, and neuroblastoma tumor cell lines. 4-Oxofenretinide causes a marked accumulation of cells in G2-M. 4-Oxofenretinide induces cancer cell apoptosis through caspase-9[1].

Name	(2E,4E,6E,8E)-N-(4-hydroxyphenyl)-3,7-dimethyl-9-(2,6,6-trimethyl-3-oxocyclohexen-1-yl)nona-2,4,6,8-tetraenamide
Synonym	More Synonyms

Description	4-Oxofenretinide (4-Oxo-4-HPR) is a metabolite of Fenretinide (HY-15373). 4-Oxofenretinide induces cell growth inhibition in ovarian, breast, and neuroblastoma tumor cell lines. 4-Oxofenretinide causes a marked accumulation of cells in G2-M. 4-Oxofenretinide induces cancer cell apoptosis through caspase-9[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Signaling Pathways >> Others >> Others
References	[1]. VillaniMG, et al. 4-oxo-fenretinide, a recently identified fenretinide metabolite,induces marked G2-M cell cycle arrest and apoptosis in fenretinide-sensitiveand fenretinide-resistant cell lines. Cancer Res. 2006 Mar 15;66(6):3238-47. [2]. Villani MG, et al. 4-oxo-fenretinide, a recently identified fenretinide metabolite, induces marked G2-M cell cycle arrest and apoptosis in fenretinide-sensitive and fenretinide-resistant cell lines. Cancer Res. 2006 Mar 15;66(6):3238-47.

Description

Related Catalog

Signaling Pathways >> Apoptosis >> Apoptosis

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

References

[1]. VillaniMG, et al. 4-oxo-fenretinide, a recently identified fenretinide metabolite,induces marked G2-M cell cycle arrest and apoptosis in fenretinide-sensitiveand fenretinide-resistant cell lines. Cancer Res. 2006 Mar 15;66(6):3238-47.

[2]. Villani MG, et al. 4-oxo-fenretinide, a recently identified fenretinide metabolite, induces marked G2-M cell cycle arrest and apoptosis in fenretinide-sensitive and fenretinide-resistant cell lines. Cancer Res. 2006 Mar 15;66(6):3238-47.

Density	1.131g/cm3
Boiling Point	641.8ºC at 760 mmHg
Molecular Formula	C₂₆H₃₁NO₃
Molecular Weight	405.53
Flash Point	341.9ºC
Exact Mass	405.23000
PSA	66.40000
LogP	6.11430
Index of Refraction	1.615
Storage condition	-20℃

4-oxo-4-HPR

N-(4-Hydroxyphenyl)-4-oxoretinamide

4-oxo-N-(4-hydroxyphenyl)retinamide

3-Keto fenretinide

4-Oxo Fenretinide

4-Keto-4-HPR

DC Chemicals Limited
China
Product Name: 4-oxo-4-HPR
Price: $400.0/100mg $700.0/250mg $1450.0/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 3-Keto fenretinide
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

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4-oxo-4-HPR

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