SLEC-11

Modify Date: 2024-01-15 01:39:15

SLEC-11 Structure
SLEC-11 structure
Common Name SLEC-11
CAS Number 863761-17-5 Molecular Weight 296.34
Density N/A Boiling Point N/A
Molecular Formula C18H17FN2O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of SLEC-11


SLEC-11 acts as a potential synthetic lethal lead for the treatment of gastric cancer. AL-GDa62 shows EC50 of 12.2 μM and 8.2 μM for isogenic mammary epithelial cells MCF10A-WT (wild-type) and MCF10A-CDH1-/-[1].

 Names

Name SLEC-11

 SLEC-11 Biological Activity

Description SLEC-11 acts as a potential synthetic lethal lead for the treatment of gastric cancer. AL-GDa62 shows EC50 of 12.2 μM and 8.2 μM for isogenic mammary epithelial cells MCF10A-WT (wild-type) and MCF10A-CDH1-/-[1].
Related Catalog
References

[1]. Andreas Luxenburger, et al. Discovery of AL-GDa62 as a Potential Synthetic Lethal Lead for the Treatment of Gastric Cancer. J Med Chem. 2021 Dec 23;64(24):18114-18142.

 Chemical & Physical Properties

Molecular Formula C18H17FN2O
Molecular Weight 296.34
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