SLEC-11

Names

[ Name ]:
SLEC-11

Biological Activity

[Description]:

SLEC-11 acts as a potential synthetic lethal lead for the treatment of gastric cancer. AL-GDa62 shows EC50 of 12.2 μM and 8.2 μM for isogenic mammary epithelial cells MCF10A-WT (wild-type) and MCF10A-CDH1-/-[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[References]

[1]. Andreas Luxenburger, et al. Discovery of AL-GDa62 as a Potential Synthetic Lethal Lead for the Treatment of Gastric Cancer. J Med Chem. 2021 Dec 23;64(24):18114-18142.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₈H₁₇FN₂O

[ Molecular Weight ]:
296.34

Related Compounds

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