Salvinorin B Mesylate

Modify Date: 2024-01-12 20:50:29

Salvinorin B Mesylate structure	Common Name	Salvinorin B Mesylate
	CAS Number	862073-79-8	Molecular Weight	468.52
	Density	1.4±0.1 g/cm3	Boiling Point	649.4±55.0 °C at 760 mmHg
	Molecular Formula	C₂₂H₂₈O₉S	Melting Point	N/A
	MSDS	N/A	Flash Point	346.6±31.5 °C

Use of Salvinorin B Mesylate

Mesyl Salvinorin B is a potent and selective kappa opioid receptor (KOP-r) agonist. Mesyl Salvinorin B prevents the ADE (Alcohol deprivation effect) in mice. Mesyl Salvinorin B dose-dependently reduces alcohol intake and preference in CED (chronic escalation drinking) mice[1][2].

Name	Salvinorin B Mesylate
Synonym	More Synonyms

Description	Mesyl Salvinorin B is a potent and selective kappa opioid receptor (KOP-r) agonist. Mesyl Salvinorin B prevents the ADE (Alcohol deprivation effect) in mice. Mesyl Salvinorin B dose-dependently reduces alcohol intake and preference in CED (chronic escalation drinking) mice[1][2].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Opioid Receptor Research Areas >> Metabolic Disease Signaling Pathways >> Neuronal Signaling >> Opioid Receptor
References	[1]. Zhou Y, et al. Effects of mesyl salvinorin B alone and in combination with naltrexone on alcohol deprivation effect in male and female mice. Neurosci Lett. 2018 Apr 23;673:19-23. [2]. Zhou Y, et al. Synergistic blockade of alcohol escalation drinking in mice by a combination of novel kappa opioid receptor agonist Mesyl Salvinorin B and naltrexone. Brain Res. 2017 May 1;1662:75-86.

Description

Related Catalog

Signaling Pathways >> GPCR/G Protein >> Opioid Receptor

Research Areas >> Metabolic Disease

Signaling Pathways >> Neuronal Signaling >> Opioid Receptor

References

[1]. Zhou Y, et al. Effects of mesyl salvinorin B alone and in combination with naltrexone on alcohol deprivation effect in male and female mice. Neurosci Lett. 2018 Apr 23;673:19-23.

[2]. Zhou Y, et al. Synergistic blockade of alcohol escalation drinking in mice by a combination of novel kappa opioid receptor agonist Mesyl Salvinorin B and naltrexone. Brain Res. 2017 May 1;1662:75-86.

Density	1.4±0.1 g/cm3
Boiling Point	649.4±55.0 °C at 760 mmHg
Molecular Formula	C₂₂H₂₈O₉S
Molecular Weight	468.52
Flash Point	346.6±31.5 °C
Exact Mass	468.145416
LogP	1.08
Vapour Pressure	0.0±1.9 mmHg at 25°C
Index of Refraction	1.561

methyl (2S,4aR,6aR,7R,9S,10aS,10bR)-2-(furan-3-yl)-6a,10b-dimethyl-9-[(methylsulfonyl)oxy]-4,10-dioxododecahydro-2H-benzo[f]isochromene-7-carboxylate

Salvinorin B Mesylate

2H-Naphtho[2,1-c]pyran-7-carboxylic acid, 2-(3-furanyl)dodecahydro-6a,10b-dimethyl-9-[(methylsulfonyl)oxy]-4,10-dioxo-, methyl ester, (2S,4aR,6aR,7R,9S,10aS,10bR)-

Methyl (2S,4aR,6aR,7R,9S,10aS,10bR)-2-(3-furyl)-6a,10b-dimethyl-9-[(methylsulfonyl)oxy]-4,10-dioxododecahydro-2H-benzo[f]isochromene-7-carboxylate

Salvinorin B Mesylate

Use of Salvinorin B Mesylate

Names

Salvinorin B Mesylate Biological Activity

Chemical & Physical Properties

Synonyms