2'-Deoxy-6-O-[2-(4-nitrophenyl)ethyl]guanosine

Modify Date: 2024-01-14 11:41:46

2'-Deoxy-6-O-[2-(4-nitrophenyl)ethyl]guanosine structure	Common Name	2'-Deoxy-6-O-[2-(4-nitrophenyl)ethyl]guanosine
	CAS Number	86137-72-6	Molecular Weight	416.39
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₈H₂₀N₆O₆	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of 2'-Deoxy-6-O-[2-(4-nitrophenyl)ethyl]guanosine

2’-Deoxy-O6-[2-(4-nitrophenylethyl)]guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	2'-deoxy-O6-[2-(4-nitrophenyl)ethyl]guanosine
Synonym	More Synonyms

Description	2’-Deoxy-O6-[2-(4-nitrophenylethyl)]guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Molecular Formula	C₁₈H₂₀N₆O₆
Molecular Weight	416.39
Exact Mass	416.14400
PSA	174.36000
LogP	1.68330

2-amino-6-(2-(p...

CAS#:108310-92-5

2'-Deoxy-6-O-[2...

CAS#:86137-72-6

Literature: He; Krawczyk; Swaminathan; Shea; Dougherty; Terhorst; Law; Griffin; Coutre; Bischofberger Journal of medicinal chemistry, 1998 , vol. 41, # 13 p. 2234 - 2242