tert-butyl 6-methoxy-3,4-dihydroisoquinoline-2(1H)-carboxylate

Modify Date: 2024-01-09 17:07:30

tert-butyl 6-methoxy-3,4-dihydroisoquinoline-2(1H)-carboxylate Structure
tert-butyl 6-methoxy-3,4-dihydroisoquinoline-2(1H)-carboxylate structure
Common Name tert-butyl 6-methoxy-3,4-dihydroisoquinoline-2(1H)-carboxylate
CAS Number 860436-57-3 Molecular Weight 263.33200
Density 1.104g/cm3 Boiling Point 375.326ºC at 760 mmHg
Molecular Formula C15H21NO3 Melting Point N/A
MSDS N/A Flash Point 180.791ºC

 Names

Name tert-butyl 6-methoxy-3,4-dihydro-1H-isoquinoline-2-carboxylate

 Chemical & Physical Properties

Density 1.104g/cm3
Boiling Point 375.326ºC at 760 mmHg
Molecular Formula C15H21NO3
Molecular Weight 263.33200
Flash Point 180.791ºC
Exact Mass 263.15200
PSA 38.77000
LogP 2.92630
Index of Refraction 1.528

 Safety Information

HS Code 2933499090

 Synthetic Route

~48%

tert-butyl 6-methoxy-3,4-dihydroisoquinoline-2(1H)-carboxylate Structure

tert-butyl 6-me...

CAS#:860436-57-3

Literature: RESPIRATORIUS AB Patent: WO2007/11290 A1, 2007 ; Location in patent: Page/Page column 25-26 ; WO 2007/011290 A1

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tert-butyl 6-methoxy-3,4-dihydroisoquinoline-2(1H)-carboxylate Structure

tert-butyl 6-me...

CAS#:860436-57-3

Literature: ABBOTT LABORATORIES; ABBOTT LABORATORIES TRADING (SHANGHAI) COMPANY, LTD.; VASUDEVAN, Anil; PENNING, Thomas Dale; CHEN, Huanming; LIANG, Bo; WANG, Shaohui; ZHAO, Zhongqiang; CHAI, Dikun; YANG, Leifu; GAO, Yingxiang Patent: WO2012/97682 A1, 2012 ; Location in patent: Page/Page column 134 ;

~%

tert-butyl 6-methoxy-3,4-dihydroisoquinoline-2(1H)-carboxylate Structure

tert-butyl 6-me...

CAS#:860436-57-3

Literature: Skogvall, Staffan; Bjork, Henrik; Berglund, Per Magnus; Dalence Guzman, Maria Fanny; Sterner, Olov Patent: US2005/165004 A1, 2005 ; Location in patent: Page/Page column 8 ;

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tert-butyl 6-methoxy-3,4-dihydroisoquinoline-2(1H)-carboxylate Structure

tert-butyl 6-me...

CAS#:860436-57-3

Literature: Dalence-Guzman, Maria F.; Berglund, Magnus; Skogvall, Staffan; Sterner, Olov Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 5 p. 2499 - 2512

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tert-butyl 6-methoxy-3,4-dihydroisoquinoline-2(1H)-carboxylate Structure

tert-butyl 6-me...

CAS#:860436-57-3

Literature: ABBOTT LABORATORIES; ABBOTT LABORATORIES TRADING (SHANGHAI) COMPANY, LTD.; VASUDEVAN, Anil; PENNING, Thomas Dale; CHEN, Huanming; LIANG, Bo; WANG, Shaohui; ZHAO, Zhongqiang; CHAI, Dikun; YANG, Leifu; GAO, Yingxiang Patent: WO2012/97682 A1, 2012 ; Title/Abstract Full Text Show Details ABBOTT LABORATORIES; ABBOTT LABORATORIES TRADING (SHANGHAI) COMPANY, LTD.; VASUDEVAN, Anil; PENNING, Thomas Dale; CHEN, Huanming; LIANG, Bo; WANG, Shaohui; WU, Fengchun; SHEN, Yan; LIU, Cuihua; ZOU, Zhenguang Patent: WO2012/97684 A1, 2012 ; WO 2012/097684 A1

~%

tert-butyl 6-methoxy-3,4-dihydroisoquinoline-2(1H)-carboxylate Structure

tert-butyl 6-me...

CAS#:860436-57-3

Literature: ABBOTT LABORATORIES; ABBOTT LABORATORIES TRADING (SHANGHAI) COMPANY, LTD.; VASUDEVAN, Anil; PENNING, Thomas Dale; CHEN, Huanming; LIANG, Bo; WANG, Shaohui; ZHAO, Zhongqiang; CHAI, Dikun; YANG, Leifu; GAO, Yingxiang Patent: WO2012/97682 A1, 2012 ; Title/Abstract Full Text Show Details ABBOTT LABORATORIES; ABBOTT LABORATORIES TRADING (SHANGHAI) COMPANY, LTD.; VASUDEVAN, Anil; PENNING, Thomas Dale; CHEN, Huanming; LIANG, Bo; WANG, Shaohui; WU, Fengchun; SHEN, Yan; LIU, Cuihua; ZOU, Zhenguang Patent: WO2012/97684 A1, 2012 ; WO 2012/097684 A1

 Customs

HS Code 2933499090
Summary 2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
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