1,3-Dipropyl-8-phenylxanthine

Modify Date: 2024-02-24 18:07:28

1,3-Dipropyl-8-phenylxanthine structure	Common Name	1,3-Dipropyl-8-phenylxanthine
	CAS Number	85872-53-3	Molecular Weight	312.36600
	Density	1.218g/cm3	Boiling Point	539.1ºC at 760 mmHg
	Molecular Formula	C₁₇H₂₀N₄O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	279.8ºC

Use of 1,3-Dipropyl-8-phenylxanthine

NPC 200 is a potent and selective antagonist of Adenosine A1 Receptor. NPC 200 reverses NECA-induced left and right atrial depression with EC50s of 1.08 and 2.03 μM[1].

Name	1,3-Dipropyl-8-phenylxanthine
Synonym	More Synonyms

Description	NPC 200 is a potent and selective antagonist of Adenosine A1 Receptor. NPC 200 reverses NECA-induced left and right atrial depression with EC50s of 1.08 and 2.03 μM[1].
Related Catalog	Research Areas >> Inflammation/Immunology Signaling Pathways >> GPCR/G Protein >> Adenosine Receptor
References	[1]. P. V. Kaplita, et al. NPC 205 is a potent and selective adenosine A1, receptor antagonist: Correlation among receptor binding, biochemical, and physiological assays. , 20(4), 429–443.

Density	1.218g/cm3
Boiling Point	539.1ºC at 760 mmHg
Molecular Formula	C₁₇H₂₀N₄O₂
Molecular Weight	312.36600
Flash Point	279.8ºC
Exact Mass	312.15900
PSA	72.68000
LogP	2.37330
Index of Refraction	1.587

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UO8430880

CHEMICAL NAME :: 1H-Purine-2,6,dione, 3,7-dihydro-1,3-dipropyl-8-phenyl-

CAS REGISTRY NUMBER :: 85872-53-3

LAST UPDATED :: 199806

DATA ITEMS CITED :: 1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >250 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #5032593

HS Code	2933990090

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

dione,3,7-dihydro-1,3-dipropyl-8-phenyl-1h-purine-6

3,9-Dihydro-8-phenyl-1,3-dipropyl-1H-purine-2,6-dione

1,3-dipropyl-8-phenyl xanthine

NPC-200

3,7-dihydro-1,3-dipropyl-8-phenyl-1h-purine-2,6,dione

1,3-Dipropyl-8-phenylxanthine

Use of 1,3-Dipropyl-8-phenylxanthine

Names

1,3-Dipropyl-8-phenylxanthine Biological Activity

Chemical & Physical Properties

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

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Synonyms