8-Methyl-2’-deoxyguanosine

Modify Date: 2024-10-09 20:01:16

8-Methyl-2’-deoxyguanosine Structure
8-Methyl-2’-deoxyguanosine structure
Common Name 8-Methyl-2’-deoxyguanosine
CAS Number 85819-69-8 Molecular Weight 281.27
Density N/A Boiling Point N/A
Molecular Formula C11H15N5O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 8-Methyl-2’-deoxyguanosine


8-Methyl-2’-deoxyguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 2-amino-9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-8-methyl-3H-purin-6-one
Synonym More Synonyms

 8-Methyl-2’-deoxyguanosine Biological Activity

Description 8-Methyl-2’-deoxyguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Molecular Formula C11H15N5O4
Molecular Weight 281.27
Exact Mass 281.11200
PSA 140.27000

 Precursor & DownStream

Precursor  0

DownStream  1

 Synonyms

Guanosine,2'-deoxy-8-methyl