Rhodionin

Modify Date: 2025-08-27 12:19:45

Rhodionin structure	Common Name	Rhodionin
	CAS Number	85571-15-9	Molecular Weight	448.377
	Density	1.7±0.1 g/cm3	Boiling Point	802.9±65.0 °C at 760 mmHg
	Molecular Formula	C₂₁H₂₀O₁₁	Melting Point	N/A
	MSDS	N/A	Flash Point	284.4±27.8 °C

Use of Rhodionin

Rhodionin, isolated from the root of Rhodiola crenulata, is a specific non-competitive cytochrome P450 2D6 inhibitor with an IC50 of 0.761 μM and a Ki of 0.769 μM[1]. Rhodionin exhibits potent, dose-dependent inhibitory effects on acetylcholinesterase (AChE) with IC50 ranged from 57.50 to 2.43 μg/mL[2]. Rhodionin exhibits potent DPPH free radical scavenging activities, with an IC50 of 19.49 μM[3].

Name	3,5,8-trihydroxy-2-(4-hydroxyphenyl)-7-(3,4,5-trihydroxy-6-methyloxan-2-yl)oxychromen-4-one
Synonym	More Synonyms

Description	Rhodionin, isolated from the root of Rhodiola crenulata, is a specific non-competitive cytochrome P450 2D6 inhibitor with an IC50 of 0.761 μM and a Ki of 0.769 μM[1]. Rhodionin exhibits potent, dose-dependent inhibitory effects on acetylcholinesterase (AChE) with IC50 ranged from 57.50 to 2.43 μg/mL[2]. Rhodionin exhibits potent DPPH free radical scavenging activities, with an IC50 of 19.49 μM[3].
Related Catalog	Research Areas >> Metabolic Disease Signaling Pathways >> Neuronal Signaling >> AChE
Target	IC50: 0.761 μM (cytochrome P450 2D6)[1]；57.50-2.43 μg/mL (AChE)[2]；19.49 μM (DPPH free radical scavenging)[3]
References	[1]. Xu W, et al. Two potent cytochrome P450 2D6 inhibitors found in Rhodiola rosea. Pharmazie. 2013 Dec;68(12):974-6. [2]. Li FJ, et al. Molecular interaction studies of acetylcholinesterase with potential acetylcholinesterase inhibitors from the root of Rhodiola crenulata using molecular docking and isothermal titration calorimetry methods. Int J Biol Macromol. 2017 Nov;104(Pt A):527-532. [3]. Choe KI, et al. The antioxidant and anti-inflammatory effects of phenolic compounds isolated from the root of Rhodiola sachalinensis A. BOR. Molecules. 2012 Sep 27;17(10):11484-94.

Density	1.7±0.1 g/cm3
Boiling Point	802.9±65.0 °C at 760 mmHg
Molecular Formula	C₂₁H₂₀O₁₁
Molecular Weight	448.377
Flash Point	284.4±27.8 °C
Exact Mass	448.100555
PSA	190.28000
LogP	0.44
Vapour Pressure	0.0±3.0 mmHg at 25°C
Index of Refraction	1.755
Storage condition	2-8℃

Rhodionidin

CAS#:94696-40-9

Rhodionin

CAS#:85571-15-9

Literature: Chemistry of Natural Compounds, , vol. 21, # 4 p. 464 - 473 Khimiya Prirodnykh Soedinenii, , vol. 21, # 4 p. 496 - 507

Precursor 0
DownStream 1
CAS#:1570-09-8 5,7-Dihydroxy-3...

3,5,8-Trihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-7-yl 6-deoxy-α-L-mannopyranoside

4H-1-Benzopyran-4-one, 7-[(6-deoxy-α-L-mannopyranosyl)oxy]-3,5,8-trihydroxy-2-(4-hydroxyphenyl)-

Herbacetin-7-O-|A-L-rhamnopyranoside

Herbacetin 7-rhamnoside

Herbacetin-7-O-α-L-rhamnopyranoside

Rhodionin

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Rhodionin
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Rhodionin
Price: ￥1920.0/5mg
Purity: 98.0%
Delivery: 3 Day
Contact: Liu jia
Email: 2130147988@qq.com

DC Chemicals Limited
China
Product Name: Rhodionin；Herbacetin 7-O-α-rhamnopyranoside
Price: $280.0/20mg
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

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Rhodionin

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.