MB-07344
Modify Date: 2025-08-27 17:48:20
MB-07344 structure
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Common Name | MB-07344 | ||
|---|---|---|---|---|
| CAS Number | 852947-39-8 | Molecular Weight | 364.37 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C19H25O5P | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of MB-07344MB-07344 is a thyroid hormone receptor (TR)-β agonist with a binding affinity Ki of 2.17 nM[1]. |
| Name | [4-[(4-hydroxy-3-propan-2-ylphenyl)methyl]-3,5-dimethylphenoxy]methylphosphonic acid |
|---|---|
| Synonym | More Synonyms |
| Description | MB-07344 is a thyroid hormone receptor (TR)-β agonist with a binding affinity Ki of 2.17 nM[1]. |
|---|---|
| Related Catalog | |
| Target |
Ki: 2.17 nM (Thyroid hormone receptor-β)[1] |
| In Vivo | MB-07344 (0.05 mg/kg; given i.v., 3 times per week for 3 weeks) results in adjunctive and additive activity when given in combination with atorvastatin in normal rabbits[1]. Animal Model: Normal rabbits[1] Dosage: 0.05 mg/kg Administration: Given i.v., 3 times per week for 3 weeks Result: Combination with atorvastatin further reduced cholesterol. |
| References |
| Molecular Formula | C19H25O5P |
|---|---|
| Molecular Weight | 364.37 |
| Exact Mass | 364.14400 |
| PSA | 96.80000 |
| LogP | 4.23720 |
| InChIKey | SVXLLCKJKRYATC-UHFFFAOYSA-N |
| SMILES | Cc1cc(OCP(=O)(O)O)cc(C)c1Cc1ccc(O)c(C(C)C)c1 |
| unii-r1zw9h43zj |