KR-32570
Modify Date: 2025-08-25 07:16:21
KR-32570 structure
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Common Name | KR-32570 | ||
|---|---|---|---|---|
| CAS Number | 852146-75-9 | Molecular Weight | 293.706 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 474.4±55.0 °C at 760 mmHg | |
| Molecular Formula | C13H12ClN3O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 240.7±31.5 °C | |
Use of KR-32570KR-32570 is a potent sodium hydrogen exchanger NHE1 inhibitor with IC50 of 50 nM; significantly and concentration dependently improves cardiac contractile function and severe contracture in conjunction with causing a marked reduction in lactate dehydrogenase release at 1-10 uM, possesses potent cardioprotective effects in perfused rat hearts. |
| Name | KR-32570 |
|---|---|
| Synonym | More Synonyms |
| Description | KR-32570 is a potent sodium hydrogen exchanger NHE1 inhibitor with IC50 of 50 nM; significantly and concentration dependently improves cardiac contractile function and severe contracture in conjunction with causing a marked reduction in lactate dehydrogenase release at 1-10 uM, possesses potent cardioprotective effects in perfused rat hearts. |
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| References | References 1. Lee BH, et al. Eur J Pharmacol. 2005 Mar 28;511(2-3):175-82. 2. Lee S, et al. J Med Chem. 2005 Apr 21;48(8):2882-91. 3. Kim MJ, et al. Eur J Pharmacol. 2005 Nov 21;525(1-3):1-7. 4. Lee KS, et al. Arch Pharm Res. 2006 May;29(5):375-83. View Related Products by Target Sodium Channel |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 474.4±55.0 °C at 760 mmHg |
| Molecular Formula | C13H12ClN3O3 |
| Molecular Weight | 293.706 |
| Flash Point | 240.7±31.5 °C |
| Exact Mass | 293.056732 |
| LogP | 1.28 |
| Vapour Pressure | 0.0±1.2 mmHg at 25°C |
| Index of Refraction | 1.635 |
| InChIKey | DYGXZBQDLFYIFD-UHFFFAOYSA-N |
| SMILES | COc1ccc(Cl)cc1-c1ccc(C(=O)N=C(N)N)o1 |
| 2-Furancarboxamide, 5-(5-chloro-2-methoxyphenyl)-N-(diaminomethylene)- |
| 5-(5-Chloro-2-methoxyphenyl)-N-(diaminomethylene)-2-furamide |
| 5-(5-chloro-2-methoxyphenyl)-N-(diaminomethylidene)furan-2-carboxamide |
| KR-32570 |