Ritipenem

Modify Date: 2024-01-05 10:58:37

Ritipenem Structure
Ritipenem structure
Common Name Ritipenem
CAS Number 84845-57-8 Molecular Weight 288.27700
Density 1.71g/cm3 Boiling Point 659.4ºC at 760 mmHg
Molecular Formula C10H12N2O6S Melting Point N/A
MSDS N/A Flash Point 352.6ºC

 Names

Name Ritipenem
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.71g/cm3
Boiling Point 659.4ºC at 760 mmHg
Molecular Formula C10H12N2O6S
Molecular Weight 288.27700
Flash Point 352.6ºC
Exact Mass 288.04200
PSA 155.46000
Index of Refraction 1.691

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
XI0191750
CHEMICAL NAME :
4-Thia-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid, 3-(((aminocarbonyl)oxy)methyl)- 6-(1-hydroxyethyl)-7-oxo-, (5R-(5alpha,6alpha(R*)))-
CAS REGISTRY NUMBER :
84845-57-8
LAST UPDATED :
199606
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C10-H12-N2-O6-S
MOLECULAR WEIGHT :
288.30

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
>1 gm/kg
TOXIC EFFECTS :
Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis) Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Nutritional and Gross Metabolic - changes in potassium
REFERENCE :
KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 29,3475,1995 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
3500 mg/kg/7D-I
TOXIC EFFECTS :
Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis) Kidney, Ureter, Bladder - other changes in urine composition Nutritional and Gross Metabolic - changes in chlorine
REFERENCE :
KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 29,3475,1995

 Synonyms

ritipenem acoxil
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