(+/-)-CIS-3-METHYL-2-PIPERIDINECARBOXYLICACID

Modify Date: 2023-01-15 18:28:16

(+/-)-CIS-3-METHYL-2-PIPERIDINECARBOXYLICACID Structure
(+/-)-CIS-3-METHYL-2-PIPERIDINECARBOXYLICACID structure
Common Name (+/-)-CIS-3-METHYL-2-PIPERIDINECARBOXYLICACID
CAS Number 84697-22-3 Molecular Weight 508.42
Density 1.4g/cm3 Boiling Point 646.7ºC at 760 mmHg
Molecular Formula C23H23Cl2N3O4S Melting Point N/A
MSDS N/A Flash Point 344.9ºC

 Use of (+/-)-CIS-3-METHYL-2-PIPERIDINECARBOXYLICACID


Tubulozole is an orally active synthetic microtubule inhibitor. Tubulozole can be used for the research of tumor[1].

 Names

Name (+/-)-ethyl-cis-[4-[[2-(2,4-dichlorophenyl)-2-(1h-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]-methylthio]phenyl]-carbamate hydrochloride
Synonym More Synonyms

  Biological Activity

Description Tubulozole is an orally active synthetic microtubule inhibitor. Tubulozole can be used for the research of tumor[1].
Related Catalog
In Vivo Tubulozole (oral; 160 mg/kg) 在体内具有抗微管和抗肿瘤作用[1]。 Animal Model: Male CDFi (DBA/Px C3H) hybrids (18-22 g)[1]. Dosage: 160 mg/kg Administration: Oral gavage Result: Had anti-microtubular and anti-tumor effect.
References

[1]. Distelmans W, et al. Influence of the synthetic microtubule inhibitor erbulozole (P.I.N.N.) (R 55 104), a new tubulozole congener, and gamma irradiation on murine tumors in vivo. Eur J Cancer Clin Oncol. 1989;25(10):1499-1504.  

 Chemical & Physical Properties

Density 1.4g/cm3
Boiling Point 646.7ºC at 760 mmHg
Molecular Formula C23H23Cl2N3O4S
Molecular Weight 508.42
Flash Point 344.9ºC
Exact Mass 543.05500
PSA 99.91000
LogP 6.69400
Index of Refraction 1.64

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
EZ4208000
CHEMICAL NAME :
Carbamic acid, (4-(((2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethy l)-1,3-dioxolan-4-yl) methyl)thio)phenyl)-, ethyl ester, cis-(+-)-
CAS REGISTRY NUMBER :
84697-22-3
LAST UPDATED :
199012
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C23-H23-Cl2-N3-O4-S
MOLECULAR WEIGHT :
508.45

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TEST SYSTEM :
Rodent - mouse
DOSE/DURATION :
160 mg/kg
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 244,95,1990

 Synonyms

tubulozole-C hydrochloride
cis-tubulozole
CIS-TUBULOZOLE HYDROCHLORIDE
TUBULOZOLE-C
TubulozolecHCl
tubulazole
TUBULOZOLE