N-Boc-4-oxo-L-proline

Modify Date: 2025-08-22 19:37:49

N-Boc-4-oxo-L-proline Structure
N-Boc-4-oxo-L-proline structure
 Common Name N-Boc-4-oxo-L-proline
CAS Number 84348-37-8 Molecular Weight 229.230
Density 1.3±0.1 g/cm3 Boiling Point 390.8±42.0 °C at 760 mmHg
Molecular Formula C10H15NO5 Melting Point 160 °C (dec.)
MSDS Chinese USA Flash Point 190.1±27.9 °C
Symbol GHS07
GHS07		 Signal Word Warning

 Names

Name N-Boc-4-oxo-L-proline
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 390.8±42.0 °C at 760 mmHg
Melting Point 160 °C (dec.)
Molecular Formula C10H15NO5
Molecular Weight 229.230
Flash Point 190.1±27.9 °C
Exact Mass 229.095016
PSA 83.91000
LogP -0.44
Vapour Pressure 0.0±1.9 mmHg at 25°C
Index of Refraction 1.516
InChIKey CKYGSXRXTIKGAJ-ZETCQYMHSA-N
SMILES CC(C)(C)OC(=O)N1CC(=O)CC1C(=O)O

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302-H319
Precautionary Statements P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xn:Harmful;
Risk Phrases R22;R36
Safety Phrases S26
RIDADR NONH for all modes of transport
HS Code 2933990090

 Synthetic Route

Boc-Hyp-OH structure

Boc-Hyp-OH

CAS#:13726-69-7

~76%

N-Boc-4-oxo-L-proline Structure

N-Boc-4-oxo-L-p...

CAS#:84348-37-8

Literature: APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. Patent: WO2004/5249 A1, 2004 ; Location in patent: Page 30-31 ; WO 2004/005249 A1
Sulfuric acid structure

Sulfuric acid

CAS#:7664-93-9

Boc-Hyp-OH structure

Boc-Hyp-OH

CAS#:13726-69-7

~77%

N-Boc-4-oxo-L-proline Structure

N-Boc-4-oxo-L-p...

CAS#:84348-37-8

Literature: Halazy, Serge; Quattropani, Anna; Scheer, Alexander; Schwarz, Mattias; Thomas, Russell; Baxter, Antony Patent: US2003/212012 A1, 2003 ;
(S)-2-benzyl 1-tert-butyl 4-oxopyrrolidine-1,2-dicarboxylate structure

(S)-2-benzyl 1-...

CAS#:154456-97-0

~88%

N-Boc-4-oxo-L-proline Structure

N-Boc-4-oxo-L-p...

CAS#:84348-37-8

Literature: Barraclough, Paul; Hudhomme, Pietrick; Spray, Caroline A.; Young, Douglas W. Tetrahedron, 1995 , vol. 51, # 14 p. 4195 - 4212
Oxalyl chloride structure

Oxalyl chloride

CAS#:79-37-8

(trans)-1-[(1,1-dimethylethoxy)carbonyl]-4-hydroxy-L-proline structure

(trans)-1-[(1,1...

CAS#:331442-12-7

~%

N-Boc-4-oxo-L-proline Structure

N-Boc-4-oxo-L-p...

CAS#:84348-37-8

Literature: US2002/193399 A1, ;
Di-tert-butyl dicarbonate structure

Di-tert-butyl d...

CAS#:24424-99-5

~%

N-Boc-4-oxo-L-proline Structure

N-Boc-4-oxo-L-p...

CAS#:84348-37-8

Literature: Journal of Organic Chemistry, , vol. 66, # 10 p. 3593 - 3596
L-Hydroxyproline structure

L-Hydroxyproline

CAS#:51-35-4

~%

N-Boc-4-oxo-L-proline Structure

N-Boc-4-oxo-L-p...

CAS#:84348-37-8

Literature: Journal of Organic Chemistry, , vol. 66, # 10 p. 3593 - 3596
N-BOC-cis-4-Hydroxy-L-proline structure

N-BOC-cis-4-Hyd...

CAS#:87691-27-8

~%

N-Boc-4-oxo-L-proline Structure

N-Boc-4-oxo-L-p...

CAS#:84348-37-8

Literature: Canadian Journal of Chemistry, , vol. 60, # 23 p. 2903 - 2907

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

MFCD01860669
1-{[(2-Methyl-2-propanyl)oxy]carbonyl}-4-oxo-L-proline
N-Boc-4-oxo-L-proline
1,2-Pyrrolidinedicarboxylic acid, 4-oxo-, 1-(1,1-dimethylethyl) ester, (2S)-
(S)-1-Boc-4-oxo-2-pyrrolidinecarboxylic acid
T5N CVTJ AVOX1&1&1 EVQ &&S or L Form
N-t-boc-4-oxo-L-proline
(2S)-1-[(2-methylpropan-2-yl)oxycarbonyl]-4-oxopyrrolidine-2-carboxylic acid
Boc-4-oxo-Pro-OH
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