5-fluoro-3-(4-piperidinyl)-1,2-benzisoxazole

Modify Date: 2025-08-27 11:24:23

5-fluoro-3-(4-piperidinyl)-1,2-benzisoxazole Structure
5-fluoro-3-(4-piperidinyl)-1,2-benzisoxazole structure
Common Name 5-fluoro-3-(4-piperidinyl)-1,2-benzisoxazole
CAS Number 84163-64-4 Molecular Weight 220.243
Density 1.2±0.1 g/cm3 Boiling Point 359.0±42.0 °C at 760 mmHg
Molecular Formula C12H13FN2O Melting Point N/A
MSDS N/A Flash Point 170.9±27.9 °C

 Names

Name 5-fluoro-3-(4-piperidinyl)-1,2-benzisoxazole
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 359.0±42.0 °C at 760 mmHg
Molecular Formula C12H13FN2O
Molecular Weight 220.243
Flash Point 170.9±27.9 °C
Exact Mass 220.101196
PSA 38.06000
LogP 1.85
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.566
InChIKey GGRZCCWFABLKCX-UHFFFAOYSA-N
SMILES Fc1ccc2onc(C3CCNCC3)c2c1

 Safety Information

Risk Phrases 36/37/38
Safety Phrases 26-36/37/39
HS Code 2934999090

 Synthetic Route

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5-fluoro-3-(4-piperidinyl)-1,2-benzisoxazole Structure

5-fluoro-3-(4-p...

CAS#:84163-64-4

Literature: Slanina, Pavel; Bartl, Jiri Patent: US2004/97523 A1, 2004 ; Location in patent: Page/Page column 8 ;

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5-fluoro-3-(4-piperidinyl)-1,2-benzisoxazole Structure

5-fluoro-3-(4-p...

CAS#:84163-64-4

Literature: Slanina, Pavel; Bartl, Jiri Patent: US2004/97523 A1, 2004 ; Location in patent: Page/Page column 8 ;

~%

5-fluoro-3-(4-piperidinyl)-1,2-benzisoxazole Structure

5-fluoro-3-(4-p...

CAS#:84163-64-4

Literature: Yang, Shyh-Ming; Tang, Yuting; Rano, Thomas; Lu, Huajun; Kuo, Gee-Hong; Gaul, Michael D.; Li, Yaxin; Ho, George; Lang, Wensheng; Conway, James G.; Liang, Yin; Lenhard, James M.; Demarest, Keith T.; Murray, William V. Bioorganic and Medicinal Chemistry Letters, 2014 , vol. 24, # 5 p. 1437 - 1441

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5-fluoro-3-(4-piperidinyl)-1,2-benzisoxazole Structure

5-fluoro-3-(4-p...

CAS#:84163-64-4

Literature: Slanina, Pavel; Bartl, Jiri Patent: US2004/97523 A1, 2004 ; Location in patent: Page/Page column 5 ;

 Customs

HS Code 2934999090
Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

1,2-Benzisoxazole, 5-fluoro-3-(4-piperidinyl)-
5-Fluoro-3-(4-piperidinyl)-1,2-benzoxazole
5-Fluoro-3-(piperidin-4-yl)-1,2-benzoxazole
Iloperidone Impurity 3
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