WIKI4

Modify Date: 2024-01-02 14:21:53

WIKI4 Structure
WIKI4 structure
Common Name WIKI4
CAS Number 838818-26-1 Molecular Weight 521.590
Density 1.4±0.1 g/cm3 Boiling Point 783.1±70.0 °C at 760 mmHg
Molecular Formula C29H23N5O3S Melting Point N/A
MSDS USA Flash Point 427.4±35.7 °C

 Use of WIKI4


WIKI4 is a potent inhibitor of Wnt/β-catenin signaling (EC50 ~ 75 nM); inhibits auto-ADP-ribosylation of tankyrase 2 (TNKS2) (IC50 ~15 nM).

 Names

Name 1H-​Benz[de]​isoquinoline-​1,​3(2H)​-​dione, 2-​[3-​[[4-​(4-​methoxyphenyl)​-​5-​(4-​pyridinyl)​-​4H-​1,​2,​4-​triazol-​3-​yl]​thio]​propyl]​-
Synonym More Synonyms

 WIKI4 Biological Activity

Description WIKI4 is a potent inhibitor of Wnt/β-catenin signaling (EC50 ~ 75 nM); inhibits auto-ADP-ribosylation of tankyrase 2 (TNKS2) (IC50 ~15 nM).
Related Catalog
References

[1]. James RG, et al. WIKI4, a novel inhibitor of tankyrase and Wnt/?-catenin signaling. PLoS One. 2012;7(12):e50457.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 783.1±70.0 °C at 760 mmHg
Molecular Formula C29H23N5O3S
Molecular Weight 521.590
Flash Point 427.4±35.7 °C
Exact Mass 521.152161
PSA 117.20000
LogP 5.20
Appearance of Characters white to beige
Vapour Pressure 0.0±2.7 mmHg at 25°C
Index of Refraction 1.716
Storage condition ?20°C
Water Solubility DMSO: soluble10mg/mL, clear (warmed)

 Safety Information

RIDADR NONH for all modes of transport

 Synonyms

2-(3-{[4-(4-Methoxyphenyl)-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl]sulfanyl}propyl)-1H-benzo[de]isoquinoline-1,3(2H)-dione
1H-Benz[de]isoquinoline-1,3(2H)-dione, 2-[3-[[4-(4-methoxyphenyl)-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl]thio]propyl]-
wiki4
Top Suppliers:I want be here
  • DC Chemicals Limited
  • China
  • Product Name: wiki4
  • Price: $400.0/100mg $750.0/250mg $1400.0/1g
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao

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WIKI4 suppliers


Price: $83/10mM*1mLinDMSO

Reference only. check more WIKI4 price

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