4-Hydroxytetramycin A

Modify Date: 2024-01-29 17:24:50

4-Hydroxytetramycin A Structure
4-Hydroxytetramycin A structure
Common Name 4-Hydroxytetramycin A
CAS Number 82517-08-6 Molecular Weight 711.79400
Density N/A Boiling Point N/A
Molecular Formula C35H53NO14 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 4-Hydroxytetramycin A


Tetramycin B (4-Hydroxytetramycin A) is a polyene macrolide antibiotic, an antifungal active compound isolated from Streptomyces hygrospinosus var. Beijingensis. The antifungal activity of Tetramycin B is higher than that of Tetramycin A, and the C-4 hydroxyl of Tetramycin B plays an important role in its biological activity[1].

 Names

Name tetramycin B

 4-Hydroxytetramycin A Biological Activity

Description Tetramycin B (4-Hydroxytetramycin A) is a polyene macrolide antibiotic, an antifungal active compound isolated from Streptomyces hygrospinosus var. Beijingensis. The antifungal activity of Tetramycin B is higher than that of Tetramycin A, and the C-4 hydroxyl of Tetramycin B plays an important role in its biological activity[1].
Related Catalog
References

[1]. Bo Cao, et al. Genome mining of the biosynthetic gene cluster of the polyene macrolide antibiotic tetramycin and characterization of a P450 monooxygenase involved in the hydroxylation of the tetramycin B polyol segment. Chembiochem. 2012 Oct 15;13(15):2234-42.  

 Chemical & Physical Properties

Molecular Formula C35H53NO14
Molecular Weight 711.79400
Exact Mass 711.34700
PSA 258.92000
LogP 0.41050