4-Hydroxytetramycin A

Names

[ Name ]:
4-Hydroxytetramycin A

Biological Activity

[Description]:

Tetramycin B (4-Hydroxytetramycin A) is a polyene macrolide antibiotic, an antifungal active compound isolated from Streptomyces hygrospinosus var. Beijingensis. The antifungal activity of Tetramycin B is higher than that of Tetramycin A, and the C-4 hydroxyl of Tetramycin B plays an important role in its biological activity[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Fungal

[References]

[1]. Bo Cao, et al. Genome mining of the biosynthetic gene cluster of the polyene macrolide antibiotic tetramycin and characterization of a P450 monooxygenase involved in the hydroxylation of the tetramycin B polyol segment. Chembiochem. 2012 Oct 15;13(15):2234-42.

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₅H₅₃NO₁₄

[ Molecular Weight ]:
711.79400

[ Exact Mass ]:
711.34700

[ PSA ]:
258.92000

[ LogP ]:
0.41050

Related Compounds

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