FEN1-IN-6

Modify Date: 2024-01-02 17:20:47

FEN1-IN-6 Structure
FEN1-IN-6 structure
Common Name FEN1-IN-6
CAS Number 824983-84-8 Molecular Weight 324.33
Density N/A Boiling Point N/A
Molecular Formula C12H8N2O5S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of FEN1-IN-6


FEN1-IN-6 (compound 9) is a potent inhibitor of Flap endonuclease-1 (FEN1, IC50=10 nM), involving in mammalian cells to repair DNA damage. FEN1-IN-6 also targets to related endonuclease, xeroderma pigmentosum G (XPG) with an IC50 value of 23 nM[1].

 Names

Name FEN1-IN-6

 FEN1-IN-6 Biological Activity

Description FEN1-IN-6 (compound 9) is a potent inhibitor of Flap endonuclease-1 (FEN1, IC50=10 nM), involving in mammalian cells to repair DNA damage. FEN1-IN-6 also targets to related endonuclease, xeroderma pigmentosum G (XPG) with an IC50 value of 23 nM[1].
Related Catalog
References

[1]. Tumey LN, et al. The identification and optimization of a N-hydroxy urea series of flap endonuclease 1 inhibitors. Bioorg Med Chem Lett. 2005 Jan 17;15(2):277-81.  

 Chemical & Physical Properties

Molecular Formula C12H8N2O5S2
Molecular Weight 324.33
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