3α-Hydroxy pravastatin sodium

Modify Date: 2025-08-21 17:48:11

3α-Hydroxy pravastatin sodium structure	Common Name	3α-Hydroxy pravastatin sodium
	CAS Number	81093-43-8	Molecular Weight	446.51000
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₃H₃₅NaO₇	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of 3α-Hydroxy pravastatin sodium

3α-Hydroxy pravastatin sodium is the major metabolite of Pravastatin. Pravastatin is a competitive HMG-CoA reductase inhibitor[1][2].

Name	sodium,(3R,5R)-7-[(1S,2R,3S,8S,8aR)-3-hydroxy-2-methyl-8-[(2S)-2-methylbutanoyl]oxy-1,2,3,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoate
Synonym	More Synonyms

Description	3α-Hydroxy pravastatin sodium is the major metabolite of Pravastatin. Pravastatin is a competitive HMG-CoA reductase inhibitor[1][2].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> Metabolic Enzyme/Protease >> HMG-CoA Reductase (HMGCR)
References	[1]. Zhang X, Vernikovskaya DI, Wang X, et al. Quantitative determination of pravastatin and its metabolite 3α-hydroxy pravastatin in plasma and urine of pregnant patients by LC-MS/MS. Biomed Chromatogr. 2016;30(4):548‐554. [2]. Shiomi M, et al. Pravastatin sodium, a competitive inhibitor of hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase, decreases the cholesterol content of newly secreted very-low-density lipoprotein in Watanabe heritable hyperlipidemic rabbits. Metabolism. 1994;43(5):559‐564.

Description

3α-Hydroxy pravastatin sodium is the major metabolite of Pravastatin. Pravastatin is a competitive HMG-CoA reductase inhibitor[1][2].

Related Catalog

Research Areas >> Cardiovascular Disease

Signaling Pathways >> Metabolic Enzyme/Protease >> HMG-CoA Reductase (HMGCR)

References

Molecular Formula	C₂₃H₃₅NaO₇
Molecular Weight	446.51000
Exact Mass	446.22800
PSA	127.12000
LogP	1.10570
InChIKey	QMLCOLOJNAKCFF-JDXVWHIXSA-M
SMILES	CCC(C)C(=O)OC1CC=CC2=CC(O)C(C)C(CCC(O)CC(O)CC(=O)[O-])C21.[Na+]

Hazard Codes	Xn
RIDADR	NONH for all modes of transport

3alpha-Hydroxy Pravastatin Sodium Salt

3|A-Hydroxy Pravastatin Sodium Salt

UNII-TC279YC5KM

Pravastatin related compound A

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