Dexpanthenol

Modify Date: 2024-01-02 12:47:57

Dexpanthenol structure	Common Name	Dexpanthenol
	CAS Number	81-13-0	Molecular Weight	205.251
	Density	1.2±0.1 g/cm3	Boiling Point	483.6±45.0 °C at 760 mmHg
	Molecular Formula	C₉H₁₉NO₄	Melting Point	N/A
	MSDS	Chinese USA	Flash Point	246.3±28.7 °C

Use of Dexpanthenol

D-Panthenol is the biologically-active alcohol of pantothenic acid, which leads to an elevation in the amount of coenzyme A in the cell.

Name	pantothenol
Synonym	More Synonyms

Description	D-Panthenol is the biologically-active alcohol of pantothenic acid, which leads to an elevation in the amount of coenzyme A in the cell.
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
References	[1]. Oguz A, et al. Topical N-acetylcysteine improves wound healing comparable to dexpanthenol: an experimental study. Int Surg. 2015 Apr;100(4):656-61.

Density	1.2±0.1 g/cm3
Boiling Point	483.6±45.0 °C at 760 mmHg
Molecular Formula	C₉H₁₉NO₄
Molecular Weight	205.251
Flash Point	246.3±28.7 °C
Exact Mass	205.131409
PSA	89.79000
LogP	-0.92
Vapour Pressure	0.0±2.8 mmHg at 25°C
Index of Refraction	1.502

Dexpanthenol MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: ES4316000

CHEMICAL NAME :: Butyramide, 2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethyl-, D-(+)-

CAS REGISTRY NUMBER :: 81-13-0

BEILSTEIN REFERENCE NO. :: 1724947

LAST UPDATED :: 199701

DATA ITEMS CITED :: 9

MOLECULAR FORMULA :: C9-H19-N-O4

MOLECULAR WEIGHT :: 205.29

WISWESSER LINE NOTATION :: Q3MVYQX1&1&1Q

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 6(1),139,1987

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 6(1),139,1987 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 15 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 6(1),139,1987

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 9 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia, Italy) V.8-43 1953-88 For publisher information, see FRMCE8 Volume(issue)/page/year: 14,43,1959

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 7 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PSEBAA Proceedings of the Society for Experimental Biology and Medicine. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1903/04- Volume(issue)/page/year: 73,292,1950

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 4 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PSEBAA Proceedings of the Society for Experimental Biology and Medicine. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1903/04- Volume(issue)/page/year: 73,292,1950 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 80472 No. of Facilities: 1172 (estimated) No. of Industries: 7 No. of Occupations: 16 No. of Employees: 8069 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 80472 No. of Facilities: 2510 (estimated) No. of Industries: 4 No. of Occupations: 7 No. of Employees: 46519 (estimated) No. of Female Employees: 36944 (estimated)

Personal Protective Equipment	Eyeshields;Gloves
Hazard Codes	Xn: Harmful;
Risk Phrases	R36/37/38
Safety Phrases	S24/25
RIDADR	UN 2583 8/PG 2
WGK Germany	1
RTECS	ES4316000
HS Code	2924199090

3-Aminopropan-1-ol

CAS#:156-87-6

D-(-)-Pantolactone

CAS#:599-04-2

Dexpanthenol

CAS#:81-13-0

Literature: Barell-Festschr. S.86 US2413077 , ; CH227706 , ; CH239754 , ;

Precursor 2
CAS#:156-87-6 3-Aminopropan-1-ol CAS#:599-04-2 D-(-)-Pantolactone
DownStream 3
CAS#:79-83-4 D-Pantothenic acid CAS#:558-43-0 2-Methyl-1,2-pr... CAS#:1211493-82-1 [3-hydroxypropy...

HS Code	2924199090
Summary	2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Release of betaine and dexpanthenol from vitamin E modified silicone-hydrogel contact lenses.

Curr. Eye Res. 40(3) , 267-73, (2015)

To develop a contact lens system that will control the release of an osmoprotectant and a moisturizing agent with the aim to reduce symptoms of ocular dryness.Profiles of the release of osmoprotectant...

Cystoid macular oedema following Descemet membrane endothelial keratoplasty.

Br. J. Ophthalmol. 99(1) , 98-102, (2015)

To determine the incidence and potential risk factors of cystoid macular oedema (CMO) following Descemet membrane endothelial keratoplasty (DMEK) with or without simultaneous cataract surgery.In this ...

Characterization of a novel standardized human three-dimensional skin wound healing model using non-sequential fractional ultrapulsed CO2 laser treatments.

Lasers Surg. Med. 47(3) , 257-65, (2015)

At present, there is no standardized in vitro human skin model for wound healing. Therefore, our aim was to establish and characterize an in vitro/ex vivo three-dimensional (3D) wound healing model, w...

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EINECS 201-327-3

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Dexpanthenol
Price: ￥238.0/500g ￥68.0/100g
Purity: 98.0%
Stocking Period: Inquiry
Contact: Liu jia

DC Chemicals Limited
China
Product Name: D panthenol
Price: $100.0/100mg $200.0/250mg $400.0/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Dexpanthenol
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

Zhejiang Hangyu API Co., Ltd
China
Product Name: D Panthenol
Price: ￥Inquiry/1kg
Purity: 99.5%
Stocking Period: Inquiry
Contact: Vinnie

Henan Tianfu Chemical Co., Ltd.
China
Product Name: Dexpanthenol
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson

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Price: $66/10mM*1mLinDMSO

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Dexpanthenol

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