Fuziline

Modify Date: 2025-08-26 09:59:01

Use of Fuziline

Fuziline is a alkaloid isolated from the lateral roots of Aconitum carmichaelii[1].

Name	15-α-hydroxyneoline
Synonym	More Synonyms

Description	Fuziline is a alkaloid isolated from the lateral roots of Aconitum carmichaelii[1].
Related Catalog	Signaling Pathways >> Others >> Others
In Vitro	Fuziline shows activity against pentobarbital sodiuminduced cardiomyocytes damage by obviously recovering beating rhythm and increasing the cell viability[1].
In Vivo	Fuziline exhibits the mean half-life of 5.93 hours, 6.13 hours and 5.12 hours for 14 mg/kg, 2 4 mg/kg and 4 mg/kg, respectively, by oral administration in rat[2].
References	[1]. Xiong L, et al. Alkaloids isolated from the lateral root of Aconitum carmichaelii. Molecules. 2012 Aug 20;17(8):9939-46. [2]. Li YX, et al. Development and validation of a UHPLC-qTOF-MS method for quantification of fuziline in rat plasma and its application in a pharmacokinetic study. Biomed Chromatogr. 2014 Dec;28(12):1707-13.

Density	1.4±0.1 g/cm3
Boiling Point	596.9±50.0 °C at 760 mmHg
Melting Point	206-207ºC
Molecular Formula	C₂₄H₃₉NO₇
Molecular Weight	453.569
Flash Point	314.8±30.1 °C
Exact Mass	453.272644
PSA	111.85000
LogP	-1.32
Vapour Pressure	0.0±3.8 mmHg at 25°C
Index of Refraction	1.617
InChIKey	FPECZWKKKKZPPP-PVALPMDTSA-N
SMILES	CCN1CC2(COC)CCC(O)C34C5CC6C(O)C5C(O)(C(O)C6OC)C(C(OC)C23)C14
Storage condition	2-8C

(1α,6α,10α,13ξ,14α,15α,16β,17ξ)-20-Ethyl-6,16-dimethoxy-4-(methoxymethyl)aconitane-1,8,14,15-tetrol

senbusine-C

Aconitane-1,8,14,15-tetrol,20-ethyl-6,16-dimethoxy-4-(methoxymethyl)-,(1alpha,6alpha,14alpha,15alpha,16beta)

Aconitane-1,8,14,15-tetrol, 20-ethyl-6,16-dimethoxy-4-(methoxymethyl)-, (1α,6α,10α,13ξ,14α,15α,16β,17ξ)-

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Price: ￥900/1 mg

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