Pancreatin

Modify Date: 2024-01-02 15:58:43

Pancreatin Structure
Pancreatin structure
Common Name Pancreatin
CAS Number 8049-47-6 Molecular Weight 300.435
Density 1.0±0.1 g/cm3 Boiling Point 462.8±14.0 °C at 760 mmHg
Molecular Formula C20H28O2 Melting Point N/A
MSDS Chinese USA Flash Point 350.6±11.0 °C
Symbol GHS07 GHS08
GHS07, GHS08
Signal Word Danger

 Use of Pancreatin


Pancreatin is the porcine pancreas extract (PPE) which contains the main pancreatic digestive enzymes.

 Names

Name Pancreatin
Synonym More Synonyms

 Pancreatin Biological Activity

Description Pancreatin is the porcine pancreas extract (PPE) which contains the main pancreatic digestive enzymes.
Related Catalog
In Vitro Pancreatin is the porcine pancreas extract (PPE) which contains the main pancreatic digestive enzymes. The amount of free fatty acids (FFAs) titrated at pH 6.5 does increase by 120 and 28% for II-LC and IIIA-LC, respectively, when Pancreatin is increased from 150 to 900 USP U/mL, and the total extent of lipolysis increases by 79 and 28% II-LC and IIIA-LC, respectively. By elevating Pancreatin activity from 150 to 900 USPU/mL, the total extent of digestion on average for LC-LBFs increases by 51%, whereas the amount of FFAs detected at pH 6.5 increases by 55% on average. An increase in extent of digestion is also observed with increasing Pancreatin levels[1].
References

[1]. Sassene P, et al. Toward the establishment of standardized in vitro tests for lipid-based formulations, part 6: effects of varying pancreatin and calcium levels. AAPS J. 2014 Nov;16(6):1344-57.

 Chemical & Physical Properties

Density 1.0±0.1 g/cm3
Boiling Point 462.8±14.0 °C at 760 mmHg
Molecular Formula C20H28O2
Molecular Weight 300.435
Flash Point 350.6±11.0 °C
Exact Mass 300.208923
LogP 6.83
Appearance of Characters powder | beige
Vapour Pressure 0.0±2.5 mmHg at 25°C
Index of Refraction 1.556
Storage condition −20°C
Stability Stable. Incompatible with alcohols, strong acids.
Water Solubility Soluble or partly soluble in water forming a slightly turbid solution; practically insoluble in ethanol (96%) and in ether . | Soluble in water. Insoluble in alcohol and ether.

 Safety Information

Symbol GHS07 GHS08
GHS07, GHS08
Signal Word Danger
Hazard Statements H315-H319-H334-H335
Precautionary Statements P261-P284-P304 + P340-P305 + P351 + P338-P342 + P311
Hazard Codes Xn
Risk Phrases 36/37/38-42-42/43
Safety Phrases S24;S26;S36/S37;S37/S39
RIDADR NONH for all modes of transport
WGK Germany 1
RTECS RT9033000

 Articles99

More Articles
ATG16L1 phosphorylation is oppositely regulated by CSNK2/casein kinase 2 and PPP1/protein phosphatase 1 which determines the fate of cardiomyocytes during hypoxia/reoxygenation.

Autophagy 11 , 1308-25, (2015)

Recent studies have shown that the phosphorylation and dephosphorylation of ULK1 and ATG13 are related to autophagy activity. Although ATG16L1 is absolutely required for autophagy induction by affecti...

In Vitro Evaluation of Cu, Fe, and Zn Bioaccessibility in the Presence of Babassu Mesocarp.

J. Agric. Food Chem. 63 , 6331-7, (2015)

In vitro gastrointestinal digestion of babassu mesocarp in the absence and presence of milk and lignin was performed to evaluate the bioaccessibility of Cu, Fe, and Zn. Extractions using NaOH solution...

Enzymes enhance degradation of the fiber-starch-protein matrix of distillers dried grains with solubles as revealed by a porcine in vitro fermentation model and microscopy.

J. Anim. Sci. 93 , 1039-51, (2015)

Effects of treating corn and wheat distillers dried grains with solubles (DDGS) with a multicarbohydrase alone or in combination with a protease on porcine in vitro fermentation characteristics and th...

 Synonyms

(9cis)-Retinoic acid
Alitretinoin
(2E,4E,6Z,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid
9-cis-retinoic acid
intrazyme
9Z-retinoic acid
ilozyme
pankreon
9-cis-Tretinoin
Retinoic acid, (9cis)-
beefviokase
diastasevera
panteric
EINECS 232-468-9
pancrex-v
pankrotanon
9(Z)-Retinoic acid
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