Transglutaminase

Modify Date: 2024-01-13 19:19:31

Transglutaminase Structure
Transglutaminase structure
Common Name Transglutaminase
CAS Number 80146-85-6 Molecular Weight N/A
Density N/A Boiling Point N/A
Molecular Formula C27H44O3H2O Melting Point N/A
MSDS USA Flash Point N/A

 Use of Transglutaminase


Transglutaminase is an enzyme that forms crosslinks between protein molecules. Transglutaminase catalyses the formation of an isopeptide bond between the group of γ-carboxamides of glutamine residues and the first-order ε-amine groups of different compounds. Transglutaminase is involved in many physiological processes, including coagulation, antibacterial immune reactions and photosynthesis[1].

 Names

Name EC 2.3.2.13
Synonym More Synonyms

 Transglutaminase Biological Activity

Description Transglutaminase is an enzyme that forms crosslinks between protein molecules. Transglutaminase catalyses the formation of an isopeptide bond between the group of γ-carboxamides of glutamine residues and the first-order ε-amine groups of different compounds. Transglutaminase is involved in many physiological processes, including coagulation, antibacterial immune reactions and photosynthesis[1].
Related Catalog
In Vitro Transglutaminase activity can be increased by Co2+, Ba2+ and K+[1]. Microbial transglutaminases are inhibited by Zn2+, Cu2+, Hg2+ and Pb2+ ions which bind to the thiol group of cysteine in the active centre[1].

 Chemical & Physical Properties

Molecular Formula C27H44O3H2O
Appearance of Characters lyophilized powder
Storage condition −20°C
Water Solubility H2O: soluble1.0mg/mL, clear

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi
Risk Phrases 36/37/38
Safety Phrases 22-24/25-26
RIDADR NONH for all modes of transport
WGK Germany 1
RTECS MA2370000

 Articles126

More Articles
Glycation and transglutaminase mediated glycosylation of fish gelatin peptides with glucosamine enhance bioactivity.

Food Chem. 142 , 285-93, (2014)

A mixture of novel glycopeptides from glycosylation between cold water fish skin gelatin hydrolysates and glucosamine (GlcN) via transglutaminase (TGase), as well as glycation between fish gelatin hyd...

Inhibition of transglutaminase 2, a novel target for pulmonary fibrosis, by two small electrophilic molecules.

Am. J. Respir. Cell. Mol. Biol. 50(4) , 737-47, (2014)

Idiopathic pulmonary fibrosis (IPF) is characterized by progressive fibrotic destruction of normal lung architecture. Due to a lack of effective treatment options, new treatment approaches are needed....

Transglutaminase 2 interacts with syndecan-4 and CD44 at the surface of human macrophages to promote removal of apoptotic cells.

Biochim. Biophys. Acta 1853(1) , 201-12, (2015)

Tissue transglutaminase (TG2) is a multifunctional protein cross-linking enzyme that has been implicated in apoptotic cell clearance but is also important in many other cell functions including cell a...

 Synonyms

MFCD00132446
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